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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Crit+Rev+Food+Sci+Nutr 2023 ; 63 (4): 563-567 Nephropedia Template TP
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Vitamin D deficiency aggravates COVID-19: discussion of the evidence #MMPMID34384289
Dantas Damascena A; Galvao Azevedo LM; de Almeida Oliveira T; da Mota Santana J; Pereira M
We discuss the quality of the article evidence on the association between vitamin D deficiency and COVID-19, as well as updating the statistics in response to the letter to the editor regarding the same paper. Our review included 22 studies with data available in 23 articles. Using crude OR data, we observed that the chance of hospitalization was 2.16 (CI 95% = 1.42 - 2.89;) for vitamin-deficient individuals compared to non-deficient ones. However, when using the adjusted OR, it was possible to obtain a chance of 1.78 (CI 95% = 1.36-2.20). For the outcome vitamin D deficiency and death in patients with COVID-19 infection the crude association value was 1.38 (OR =1.38; CI 95% = 1.08 - 1.68) and the adjusted OR with the two studies was 1.08 (CI 95% = 0.82- 1.34). This new analyzes don't substantially alter our results. Vitamin D remains associated with severity COVID-19.