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10.1146/annurev-med-042220-011857

http://scihub22266oqcxt.onion/10.1146/annurev-med-042220-011857
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34379444!ä!34379444

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suck abstract from ncbi

pmid34379444      Annu+Rev+Med 2022 ; 73 (ä): 129-147
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  • COVID-19 and Diabetes #MMPMID34379444
  • Singh AK; Khunti K
  • Annu Rev Med 2022[Jan]; 73 (ä): 129-147 PMID34379444show ga
  • The prevalence of diabetes in people with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has varied worldwide. Most of the available evidence suggests a significant increase in severity and mortality of COVID-19 in people with either type 1 (T1DM) or type 2 diabetes mellitus (T2DM), especially in association with poor glycemic control. While new-onset hyperglycemia and new-onset diabetes (both T1DM and T2DM) have been increasingly recognized in the context of COVID-19 and have been associated with worse outcome, no conclusive evidence yet suggests direct tropism of SARS-CoV-2 on the beta cells of pancreatic islets. While all approved oral antidiabetic agents appear to be safe in people with T2DM having COVID-19, no conclusive data are yet available to indicate a mortality benefit with any class of these drugs, in the absence of large randomized controlled trials.
  • |*COVID-19[MESH]
  • |*Diabetes Mellitus, Type 2/drug therapy/epidemiology[MESH]
  • |*Hyperglycemia[MESH]
  • |Humans[MESH]
  • |Hypoglycemic Agents/therapeutic use[MESH]


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