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10.1007/s13679-021-00448-8

http://scihub22266oqcxt.onion/10.1007/s13679-021-00448-8
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suck abstract from ncbi


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pmid34374955      Curr+Obes+Rep 2021 ; 10 (3): 282-289
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  • Obesity as a Risk Factor for Severe COVID-19: Summary of the Best Evidence and Implications for Health Care #MMPMID34374955
  • Sattar N; Valabhji J
  • Curr Obes Rep 2021[Sep]; 10 (3): 282-289 PMID34374955show ga
  • PURPOSE OF REVIEW: To collate the best evidence from several strands-epidemiological, genetic, comparison with historical data and mechanistic information-and ask whether obesity is an important causal and potentially modifiable risk factor for severe COVID-19 outcomes. RECENT FINDINGS: Several hundred studies provide powerful evidence that body mass index (BMI) is a strong linear risk factor for severe COVID-19 outcomes, with recent studies suggesting ~5-10% higher risk for COVID-19 hospitalisation per every kg/m(2) higher BMI. Genetic data concur with hazard ratios increasing by 14% per every kg/m(2) higher BMI. BMI to COVID-19 links differ markedly from prior BMI-infection associations and are further supported as likely causal by multiple biologically plausible pathways. Excess adiposity appears to be an important, modifiable risk factor for adverse COVID-19 outcomes across all ethnicities. The pandemic is also worsening obesity levels. It is imperative that medical systems worldwide meet this challenge by upscaling investments in obesity prevention and treatments.
  • |*Body Mass Index[MESH]
  • |*Pandemics[MESH]
  • |*Severity of Illness Index[MESH]
  • |Adiposity[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Delivery of Health Care[MESH]
  • |Humans[MESH]
  • |Obesity/*epidemiology[MESH]
  • |Risk Factors[MESH]


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