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10.1080/21655979.2021.1952791 http://scihub22266oqcxt.onion/10.1080/21655979.2021.1952791 34369278!8806523!34369278     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bioengineered 2021 ; 12 (1): 4054-4069 Nephropedia Template TP {{tp|p=34369278|t=2021. Clinical significance and molecular mechanism of angiotensin-converting enzyme 2 in hepatocellular carcinoma tissues |pdf=|usr=}}{{34369278}} gab.com Text Clinical significance and molecular mechanism of angiotensin-converting enzyme 2 in hepatocellular carcinoma tissues JO: Bioengineered http://www.kidney.de/pget.php?&tw=1&pmid=34369278 #FOAvip During the pandemic of the coronavirus disease 2019, there exist quite a few studies on angiotensin-converting enzyme 2 (ACE2) and SARS-CoV-2 infection, while little is known about ACE2 in hepatocellular carcinoma (HCC). The detailed mechanism among ACE2 and HCC still remains unclear, which needs to be further investigated. In the current study with a total of 6,926 samples, ACE2 expression was downregulated in HCC compared with non-HCC samples (standardized mean difference = -0.41). With the area under the curve of summary receiver operating characteristic = 0.82, ACE2 expression showed a better ability to differentiate HCC from non-HCC. The mRNA expression of ACE2 was related to the age, alpha-fetoprotein levels and cirrhosis of HCC patients, and it was identified as a protected factor for HCC patients via Kaplan-Meier survival, Cox regression analyses. The potential molecular mechanism of ACE2 may be relevant to catabolic and cell division. In all, decreasing ACE2 expression can be seen in HCC, and its protective role for HCC patients and underlying mechanisms were explored in the study. Twit Text FOAVip Clinical significance and molecular mechanism of angiotensin-converting enzyme 2 in hepatocellular carcinoma tissues ????Bioengineered http://www.kidney.de/pget.php?&tw=1&pmid=34369278 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34369278 #FOAvip English Wikipedia <ref>{{Cite pmid|34369278}}</ref> Clinical significance and molecular mechanism of angiotensin-converting enzyme 2 in hepatocellular carcinoma tissues #MMPMID34369278 Huang WJ; He WY; Li JD; He RQ; Huang ZG; Zhou XG; Li JJ; Zeng DT; Chen JT; Wu WZ; Dang YW; Chen G Bioengineered 2021[Dec]; 12 (1): 4054-4069 PMID34369278show ga During the pandemic of the coronavirus disease 2019, there exist quite a few studies on angiotensin-converting enzyme 2 (ACE2) and SARS-CoV-2 infection, while little is known about ACE2 in hepatocellular carcinoma (HCC). The detailed mechanism among ACE2 and HCC still remains unclear, which needs to be further investigated. In the current study with a total of 6,926 samples, ACE2 expression was downregulated in HCC compared with non-HCC samples (standardized mean difference = -0.41). With the area under the curve of summary receiver operating characteristic = 0.82, ACE2 expression showed a better ability to differentiate HCC from non-HCC. The mRNA expression of ACE2 was related to the age, alpha-fetoprotein levels and cirrhosis of HCC patients, and it was identified as a protected factor for HCC patients via Kaplan-Meier survival, Cox regression analyses. The potential molecular mechanism of ACE2 may be relevant to catabolic and cell division. In all, decreasing ACE2 expression can be seen in HCC, and its protective role for HCC patients and underlying mechanisms were explored in the study. |Age Factors[MESH] |Aged[MESH] |Angiotensin-Converting Enzyme 2/*genetics/metabolism[MESH] |Area Under Curve[MESH] |COVID-19/virology[MESH] |Carcinoma, Hepatocellular/diagnosis/*genetics/mortality/pathology[MESH] |Databases, Genetic[MESH] |Datasets as Topic[MESH] |Female[MESH] |Gene Expression Regulation, Neoplastic[MESH] |Humans[MESH] |Liver Cirrhosis/diagnosis/*genetics/mortality/pathology[MESH] |Liver Neoplasms/diagnosis/*genetics/mortality/pathology[MESH] |Male[MESH] |Middle Aged[MESH] |Neoplasm Proteins/classification/*genetics/metabolism[MESH] |Protective Factors[MESH] |Protein Interaction Mapping[MESH] |ROC Curve[MESH] |Receptors, Virus/*genetics/metabolism[MESH] |SARS-CoV-2/pathogenicity[MESH] |Survival Analysis[MESH]Clinical significance and molecular mechanism of angiotensin-convertin(epmc).pdf DeepDyve Pubget Overpricing