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10.3389/fendo.2021.587801 http://scihub22266oqcxt.onion/10.3389/fendo.2021.587801 34367059!8342037!34367059     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Endocrinol+(Lausanne) 2021 ; 12 (ä): 587801 Nephropedia Template TP {{tp|p=34367059|t=2021. Metformin and Covid-19: Focused Review of Mechanisms and Current Literature Suggesting Benefit |pdf=|usr=}}{{34367059}} gab.com Text Metformin and Covid-19: Focused Review of Mechanisms and Current Literature Suggesting Benefit JO: Front Endocrinol (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=34367059 #FOAvip Metformin is the first-line medication for type 2 diabetes, but it also has a long history of improved outcomes in infectious diseases, such as influenza, hepatitis C, and in-vitro assays of zika. In the current Covid-19 pandemic, which has rapidly spread throughout the world, 4 observational studies have been published showing reduced mortality among individuals with home metformin use. There are several potential overlapping mechanisms by which metformin may reduce mortality from Covid-19. Metformin's past anti-infectious benefits have been both against the infectious agent directly, as well as by improving the underlying health of the human host. It is unknown if the lower mortality suggested by observational studies in patients infected with Covid-19 who are on home metformin is due to direct activity against the virus itself, improved host substrate, or both. Twit Text FOAVip Metformin and Covid-19: Focused Review of Mechanisms and Current Literature Suggesting Benefit ????Front Endocrinol (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=34367059 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34367059 #FOAvip English Wikipedia <ref>{{Cite pmid|34367059}}</ref> Metformin and Covid-19: Focused Review of Mechanisms and Current Literature Suggesting Benefit #MMPMID34367059 Ibrahim S; Lowe JR; Bramante CT; Shah S; Klatt NR; Sherwood N; Aronne L; Puskarich M; Tamariz L; Palacio A; Bomberg E; Usher M; King S; Benson B; Vojta D; Tignanelli C; Ingraham N Front Endocrinol (Lausanne) 2021[]; 12 (ä): 587801 PMID34367059show ga Metformin is the first-line medication for type 2 diabetes, but it also has a long history of improved outcomes in infectious diseases, such as influenza, hepatitis C, and in-vitro assays of zika. In the current Covid-19 pandemic, which has rapidly spread throughout the world, 4 observational studies have been published showing reduced mortality among individuals with home metformin use. There are several potential overlapping mechanisms by which metformin may reduce mortality from Covid-19. Metformin's past anti-infectious benefits have been both against the infectious agent directly, as well as by improving the underlying health of the human host. It is unknown if the lower mortality suggested by observational studies in patients infected with Covid-19 who are on home metformin is due to direct activity against the virus itself, improved host substrate, or both. |*COVID-19 Drug Treatment[MESH] |Humans[MESH] |Hypoglycemic Agents/*therapeutic use[MESH] |Metformin/*therapeutic use[MESH]Metformin and Covid-19: Focused Review of Mechanisms and Current Liter(epmc).pdf DeepDyve Pubget Overpricing