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10.1016/j.compbiomed.2021.104689

http://scihub22266oqcxt.onion/10.1016/j.compbiomed.2021.104689
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suck abstract from ncbi


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pmid34364263      Comput+Biol+Med 2021 ; 136 (ä): 104689
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  • CoLe-CNN+: Context learning - Convolutional neural network for COVID-19-Ground-Glass-Opacities detection and segmentation #MMPMID34364263
  • Pezzano G; Diaz O; Ripoll VR; Radeva P
  • Comput Biol Med 2021[Sep]; 136 (ä): 104689 PMID34364263show ga
  • BACKGROUND AND OBJECTIVE: The most common tool for population-wide COVID-19 identification is the Reverse Transcription-Polymerase Chain Reaction test that detects the presence of the virus in the throat (or sputum) in swab samples. This test has a sensitivity between 59% and 71%. However, this test does not provide precise information regarding the extension of the pulmonary infection. Moreover, it has been proven that through the reading of a computed tomography (CT) scan, a clinician can provide a more complete perspective of the severity of the disease. Therefore, we propose a comprehensive system for fully-automated COVID-19 detection and lesion segmentation from CT scans, powered by deep learning strategies to support decision-making process for the diagnosis of COVID-19. METHODS: In the workflow proposed, the input CT image initially goes through lung delineation, then COVID-19 detection and finally lesion segmentation. The chosen neural network has a U-shaped architecture using a newly introduced Multiple Convolutional Layers structure, that produces a lung segmentation mask within a novel pipeline for direct COVID-19 detection and segmentation. In addition, we propose a customized loss function that guarantees an optimal balance on average between sensitivity and precision. RESULTS: Lungs' segmentation results show a sensitivity near 99% and Dice-score of 97%. No false positives were observed in the detection network after 10 different runs with an average accuracy of 97.1%. The average accuracy for lesion segmentation was approximately 99%. Using UNet as a benchmark, we compared our results with several other techniques proposed in the literature, obtaining the largest improvement over the UNet outcomes. CONCLUSIONS: The method proposed in this paper outperformed the state-of-the-art methods for COVID-19 lesion segmentation from CT images, and improved by 38.2% the results for F1-score of UNet. The high accuracy observed in this work opens up a wide range of possible applications of our algorithm in other fields related to medical image segmentation.
  • |*COVID-19[MESH]
  • |Humans[MESH]
  • |Image Processing, Computer-Assisted[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Neural Networks, Computer[MESH]
  • |SARS-CoV-2[MESH]


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