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10.1016/j.celrep.2021.109518 http://scihub22266oqcxt.onion/10.1016/j.celrep.2021.109518 34358460!8342976!34358460     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2021 ; 36 (6): 109518 Nephropedia Template TP {{tp|p=34358460|t=2021. Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms |pdf=|usr=}}{{34358460}} gab.com Text Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=34358460 #FOAvip We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses, soluble markers of inflammation, and antibody levels and neutralization capacity longitudinally in 70 individuals with PCR-confirmed SARS-CoV-2 infection. Participants represent a spectrum of illness and recovery, including some with persistent viral shedding in saliva and many experiencing post-acute sequelae of SARS-CoV-2 infection (PASC). T cell responses remain stable for up to 9 months. Whereas the magnitude of early CD4(+) T cell immune responses correlates with severity of initial infection, pre-existing lung disease is independently associated with higher long-term SARS-CoV-2-specific CD8(+) T cell responses. Among participants with PASC 4 months following coronavirus disease 2019 (COVID-19) symptom onset, we observe a lower frequency of CD8(+) T cells expressing CD107a, a marker of degranulation, in response to Nucleocapsid (N) peptide pool stimulation, and a more rapid decline in the frequency of N-specific interferon-gamma-producing CD8(+) T cells. Neutralizing antibody levels strongly correlate with SARS-CoV-2-specific CD4(+) T cell responses. Twit Text FOAVip Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=34358460 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34358460 #FOAvip English Wikipedia <ref>{{Cite pmid|34358460}}</ref> Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms #MMPMID34358460 Peluso MJ; Deitchman AN; Torres L; Iyer NS; Munter SE; Nixon CC; Donatelli J; Thanh C; Takahashi S; Hakim J; Turcios K; Janson O; Hoh R; Tai V; Hernandez Y; Fehrman EA; Spinelli MA; Gandhi M; Trinh L; Wrin T; Petropoulos CJ; Aweeka FT; Rodriguez-Barraquer I; Kelly JD; Martin JN; Deeks SG; Greenhouse B; Rutishauser RL; Henrich TJ Cell Rep 2021[Aug]; 36 (6): 109518 PMID34358460show ga We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses, soluble markers of inflammation, and antibody levels and neutralization capacity longitudinally in 70 individuals with PCR-confirmed SARS-CoV-2 infection. Participants represent a spectrum of illness and recovery, including some with persistent viral shedding in saliva and many experiencing post-acute sequelae of SARS-CoV-2 infection (PASC). T cell responses remain stable for up to 9 months. Whereas the magnitude of early CD4(+) T cell immune responses correlates with severity of initial infection, pre-existing lung disease is independently associated with higher long-term SARS-CoV-2-specific CD8(+) T cell responses. Among participants with PASC 4 months following coronavirus disease 2019 (COVID-19) symptom onset, we observe a lower frequency of CD8(+) T cells expressing CD107a, a marker of degranulation, in response to Nucleocapsid (N) peptide pool stimulation, and a more rapid decline in the frequency of N-specific interferon-gamma-producing CD8(+) T cells. Neutralizing antibody levels strongly correlate with SARS-CoV-2-specific CD4(+) T cell responses. |Adult[MESH] |Antibodies, Neutralizing/immunology[MESH] |Antibodies, Viral/immunology[MESH] |CD8-Positive T-Lymphocytes/immunology[MESH] |COVID-19/*complications/*immunology/pathology[MESH] |Disease Progression[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Post-Acute COVID-19 Syndrome[MESH] |SARS-CoV-2/*immunology[MESH] |Severity of Illness Index[MESH]Long-term SARS-CoV-2-specific immune and inflammatory responses in ind(epmc).pdf DeepDyve Pubget Overpricing