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10.1111/cen.14566 http://scihub22266oqcxt.onion/10.1111/cen.14566 34358373!8444815!34358373     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Endocrinol+(Oxf) 2023 ; 99 (5): 470-473 Nephropedia Template TP {{tp|p=34358373|t=2023. ChAdOx1 SARS-CoV-2 vaccination: A putative precipitant of adrenal crises |pdf=|usr=}}{{34358373}} gab.com Text ChAdOx1 SARS-CoV-2 vaccination: A putative precipitant of adrenal crises JO: Clin Endocrinol (Oxf) http://www.kidney.de/pget.php?&tw=1&pmid=34358373 #FOAvip BACKGROUND: Patients with adrenal insufficiency (AI) have excess mortality, in part due to the occurrence of life-threatening adrenal crises. Infective processes, including that of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are recognised as the major precipitant of adrenal crises. Adverse reactions to the ChAdOx1 SARS-CoV-2 vaccine occur in a significant proportion of individuals, however, are mild-moderate in the majority of cases. DESIGN: Case series. PATIENTS & RESULTS: We describe five cases where more severe adverse reactions to the ChAdOx1 SARS-CoV-2 vaccine led to actual or incipient adrenal crises requiring parenteral hydrocortisone within 24 h of receiving the first ChAdOx1 SARS-CoV-2 vaccination. CONCLUSION: In individuals with adrenal insufficiency, adverse reactions to the initial dose of the ChAdOx1 SARS-CoV-2 vaccination can precipitate adrenal crises. We recommend that patients with AI should immediately increase their maintenance glucocorticoid dosage 2-3 fold on experiencing any symptoms in the initial 24 h following vaccination. Twit Text FOAVip ChAdOx1 SARS-CoV-2 vaccination: A putative precipitant of adrenal crises ????Clin Endocrinol (Oxf) http://www.kidney.de/pget.php?&tw=1&pmid=34358373 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34358373 #FOAvip English Wikipedia <ref>{{Cite pmid|34358373}}</ref> ChAdOx1 SARS-CoV-2 vaccination: A putative precipitant of adrenal crises #MMPMID34358373 Maguire D; McLaren DS; Rasool I; Shah PM; Lynch J; Murray RD Clin Endocrinol (Oxf) 2023[Nov]; 99 (5): 470-473 PMID34358373show ga BACKGROUND: Patients with adrenal insufficiency (AI) have excess mortality, in part due to the occurrence of life-threatening adrenal crises. Infective processes, including that of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are recognised as the major precipitant of adrenal crises. Adverse reactions to the ChAdOx1 SARS-CoV-2 vaccine occur in a significant proportion of individuals, however, are mild-moderate in the majority of cases. DESIGN: Case series. PATIENTS & RESULTS: We describe five cases where more severe adverse reactions to the ChAdOx1 SARS-CoV-2 vaccine led to actual or incipient adrenal crises requiring parenteral hydrocortisone within 24 h of receiving the first ChAdOx1 SARS-CoV-2 vaccination. CONCLUSION: In individuals with adrenal insufficiency, adverse reactions to the initial dose of the ChAdOx1 SARS-CoV-2 vaccination can precipitate adrenal crises. We recommend that patients with AI should immediately increase their maintenance glucocorticoid dosage 2-3 fold on experiencing any symptoms in the initial 24 h following vaccination. |*Adrenal Insufficiency/etiology[MESH] |*COVID-19 Vaccines/adverse effects[MESH] |*COVID-19/prevention & control[MESH] |Acute Disease[MESH] |Humans[MESH] |SARS-CoV-2[MESH]ChAdOx1 SARS-CoV-2 vaccination: A putative precipitant of adrenal cris(epmc).pdf DeepDyve Pubget Overpricing