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10.1111/1756-185X.14194 http://scihub22266oqcxt.onion/10.1111/1756-185X.14194 34347374!ä!34347374 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Rheum+Dis 2021 ; 24 (10): 1317-1320 Nephropedia Template TP {{tp|p=34347374|t=2021. A bond between rheumatic diseases and cancer in the elderly: The interleukin-6 pathway |pdf=|usr=}}{{34347374}} gab.com Text A bond between rheumatic diseases and cancer in the elderly: The interleukin-6 pathway JO: Int J Rheum Dis http://www.kidney.de/pget.php?&tw=1&pmid=34347374 #FOAvip Interleukin (IL)-6 is a soluble factor secreted by T lymphocytes, involved in antibody generation by B lymphocytes. The IL-6 pathway has risen as a pivotal pathway implicated in immune regulation and dysregulation in various rheumatic diseases. Nonetheless, elevated IL-6 levels can also play a role in cancer. Targeting the IL-6 pathway has led to innovative therapeutic approaches for rheumatic diseases and for COVID-19, particularly in the elderly. Indeed, tocilizumab, an agent targeting IL-6, has recently amassed significant attention as a promising univocal agent for different conditions. In this viewpoint, we sought to recall and describe the common pathway among osteoarthritis, rheumatoid arthritis, and cancer, suggesting that anti-IL-6 may be considered a jack-of-all-trades against inflammaging in the elderly. Twit Text FOAVip A bond between rheumatic diseases and cancer in the elderly: The interleukin-6 pathway ????Int J Rheum Dis http://www.kidney.de/pget.php?&tw=1&pmid=34347374 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34347374 #FOAvip English Wikipedia <ref>{{Cite pmid|34347374}}</ref> A bond between rheumatic diseases and cancer in the elderly: The interleukin-6 pathway #MMPMID34347374 Iorio GC; Ammendolia A; Marotta N; Ricardi U; de Sire A Int J Rheum Dis 2021[Oct]; 24 (10): 1317-1320 PMID34347374show ga Interleukin (IL)-6 is a soluble factor secreted by T lymphocytes, involved in antibody generation by B lymphocytes. The IL-6 pathway has risen as a pivotal pathway implicated in immune regulation and dysregulation in various rheumatic diseases. Nonetheless, elevated IL-6 levels can also play a role in cancer. Targeting the IL-6 pathway has led to innovative therapeutic approaches for rheumatic diseases and for COVID-19, particularly in the elderly. Indeed, tocilizumab, an agent targeting IL-6, has recently amassed significant attention as a promising univocal agent for different conditions. In this viewpoint, we sought to recall and describe the common pathway among osteoarthritis, rheumatoid arthritis, and cancer, suggesting that anti-IL-6 may be considered a jack-of-all-trades against inflammaging in the elderly. |*Immunity, Cellular[MESH] |Aged[MESH] |B-Lymphocytes/*immunology[MESH] |COVID-19/immunology/*metabolism[MESH] |Humans[MESH] |Interleukin-6/*metabolism[MESH] |Lymphocyte Count[MESH] |Neoplasms/immunology/*metabolism[MESH] |Rheumatic Diseases/immunology/*metabolism[MESH]A bond between rheumatic diseases and cancer in the elderly: The inter(epmc).pdf DeepDyve Pubget Overpricing