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10.1016/j.bbagen.2021.129974 http://scihub22266oqcxt.onion/10.1016/j.bbagen.2021.129974 34343644!8325376!34343644     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochim+Biophys+Acta+Gen+Subj 2021 ; 1865 (11): 129974 Nephropedia Template TP {{tp|p=34343644|t=2021. Nanobodies as powerful pulmonary targeted biotherapeutics against SARS-CoV-2, pharmaceutical point of view |pdf=|usr=}}{{34343644}} gab.com Text Nanobodies as powerful pulmonary targeted biotherapeutics against SARS-CoV-2, pharmaceutical point of view JO: Biochim Biophys Acta Gen Subj http://www.kidney.de/pget.php?&tw=1&pmid=34343644 #FOAvip Background Since December 2019, the newly emerged SARS-CoV-2 virus continues to infect humans and many people died from severe Covid-19 during the last 2 years worldwide. Different approaches are being used for treatment of this infection and its consequences, but limited results have been achieved and new therapeutics are still needed. One of the most interesting biotherapeutics in this era are Nanobodies which have shown very promising results in recent researches. Scope of review Here, we have reviewed the potentials of Nanobodies in Covid-19 treatment. We have also discussed the properties of these biotherapeutics that make them very suitable for pulmonary drug delivery, which seems to be very important route of administration in this disease. Major conclusion Nanobodies with their special biological and biophysical characteristics and their resistance against harsh manufacturing condition, can be considered as promising, targeted biotherapeutics which can be administered by pulmonary delivery pharmaceutical systems against Covid-19. General significance Covid-19 has become a global problem during the last two years and with emerging mutant strains, prophylactic and therapeutic approaches are still highly needed. Nanobodies with their specific properties can be considered as valuable and promising candidates in Covid-19 therapy. Twit Text FOAVip Nanobodies as powerful pulmonary targeted biotherapeutics against SARS-CoV-2, pharmaceutical point of view ????Biochim Biophys Acta Gen Subj http://www.kidney.de/pget.php?&tw=1&pmid=34343644 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34343644 #FOAvip English Wikipedia <ref>{{Cite pmid|34343644}}</ref> Nanobodies as powerful pulmonary targeted biotherapeutics against SARS-CoV-2, pharmaceutical point of view #MMPMID34343644 Najmeddin A; Bahrololoumi Shapourabadi M; Behdani M; Dorkoosh F Biochim Biophys Acta Gen Subj 2021[Nov]; 1865 (11): 129974 PMID34343644show ga Background Since December 2019, the newly emerged SARS-CoV-2 virus continues to infect humans and many people died from severe Covid-19 during the last 2 years worldwide. Different approaches are being used for treatment of this infection and its consequences, but limited results have been achieved and new therapeutics are still needed. One of the most interesting biotherapeutics in this era are Nanobodies which have shown very promising results in recent researches. Scope of review Here, we have reviewed the potentials of Nanobodies in Covid-19 treatment. We have also discussed the properties of these biotherapeutics that make them very suitable for pulmonary drug delivery, which seems to be very important route of administration in this disease. Major conclusion Nanobodies with their special biological and biophysical characteristics and their resistance against harsh manufacturing condition, can be considered as promising, targeted biotherapeutics which can be administered by pulmonary delivery pharmaceutical systems against Covid-19. General significance Covid-19 has become a global problem during the last two years and with emerging mutant strains, prophylactic and therapeutic approaches are still highly needed. Nanobodies with their specific properties can be considered as valuable and promising candidates in Covid-19 therapy. |Angiotensin-Converting Enzyme 2/antagonists & inhibitors/genetics/immunology[MESH] |Animals[MESH] |Antibodies, Neutralizing/biosynthesis/isolation & purification/*therapeutic use[MESH] |Antiviral Agents/isolation & purification/metabolism/*therapeutic use[MESH] |COVID-19/immunology/*therapy/virology[MESH] |Camelus[MESH] |Drug Delivery Systems[MESH] |Humans[MESH] |Immune Sera/chemistry[MESH] |Immunologic Factors/biosynthesis/isolation & purification/*therapeutic use[MESH] |Lung/drug effects/immunology/virology[MESH] |Molecular Targeted Therapy/methods[MESH] |Peptide Library[MESH] |Protein Binding/drug effects[MESH] |SARS-CoV-2/*drug effects/genetics/immunology[MESH] |Single-Domain Antibodies/biosynthesis/isolation & purification/*therapeutic use[MESH]Nanobodies as powerful pulmonary targeted biotherapeutics against SARS(epmc).pdf DeepDyve Pubget Overpricing