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10.1111/jcpt.13499

http://scihub22266oqcxt.onion/10.1111/jcpt.13499
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34339547!8447296!34339547
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suck abstract from ncbi


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pmid34339547      J+Clin+Pharm+Ther 2022 ; 47 (3): 407-410
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  • Elevated INR in a COVID-19 patient after concomitant administration of favipiravir and warfarin: A case report #MMPMID34339547
  • Sekimoto M; Imai T; Hidaka S; Chiba N; Sakurai A; Hata M; Kikuchi N
  • J Clin Pharm Ther 2022[Mar]; 47 (3): 407-410 PMID34339547show ga
  • WHAT IS KNOWN AND OBJECTIVE: Favipiravir is a promising treatment candidate for managing coronavirus disease 2019 (COVID-19). Warfarin has many drug interactions, but no interactions with favipiravir have been reported. CASE SUMMARY: Our patient was taking warfarin for deep vein thrombosis. The international normalized ratio (INR) was stable (1.65 to 2.0); however, it increased to 4.63 after administering favipiravir. The patient had no other factors justifying this change. WHAT IS NEW AND CONCLUSION: Favipiravir and warfarin might have previously unidentified drug interactions that elevated the INR. Therefore, INR must be closely monitored when they are concomitantly administered in COVID-19 patients.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Warfarin/therapeutic use[MESH]
  • |Amides[MESH]
  • |Anticoagulants/therapeutic use[MESH]
  • |Drug Interactions[MESH]
  • |Humans[MESH]
  • |International Normalized Ratio[MESH]


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