Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.bmc.2021.116329 http://scihub22266oqcxt.onion/10.1016/j.bmc.2021.116329 34329818!8299292!34329818     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Bioorg+Med+Chem 2021 ; 45 (ä): 116329 Nephropedia Template TP {{tp|p=34329818|t=2021. Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2 |pdf=|usr=}}{{34329818}} gab.com Text Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2 JO: Bioorg Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=34329818 #FOAvip Agrimonia pilosa (AP), Galla rhois (RG), and their mixture (APRG64) strongly inhibited SARS-CoV-2 by interfering with multiple steps of the viral life cycle including viral entry and replication. Furthermore, among 12 components identified in APRG64, three displayed strong antiviral activity, ursolic acid (1), quercetin (7), and 1,2,3,4,6-penta-O-galloyl-beta-d-glucose (12). Molecular docking analysis showed these components to bind potently to the spike receptor-binding-domain (RBD) of the SARS-CoV-2 and its variant B.1.1.7. Taken together, these findings indicate APRG64 as a potent drug candidate to treat SARS-CoV-2 and its variants. Twit Text FOAVip Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2 ????Bioorg Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=34329818 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34329818 #FOAvip English Wikipedia <ref>{{Cite pmid|34329818}}</ref> Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their components against SARS-CoV-2 #MMPMID34329818 Lee YG; Kang KW; Hong W; Kim YH; Oh JT; Park DW; Ko M; Bai YF; Seo YJ; Lee SM; Kim H; Kang SC Bioorg Med Chem 2021[Sep]; 45 (ä): 116329 PMID34329818show ga Agrimonia pilosa (AP), Galla rhois (RG), and their mixture (APRG64) strongly inhibited SARS-CoV-2 by interfering with multiple steps of the viral life cycle including viral entry and replication. Furthermore, among 12 components identified in APRG64, three displayed strong antiviral activity, ursolic acid (1), quercetin (7), and 1,2,3,4,6-penta-O-galloyl-beta-d-glucose (12). Molecular docking analysis showed these components to bind potently to the spike receptor-binding-domain (RBD) of the SARS-CoV-2 and its variant B.1.1.7. Taken together, these findings indicate APRG64 as a potent drug candidate to treat SARS-CoV-2 and its variants. |*COVID-19 Drug Treatment[MESH] |Agrimonia/*chemistry[MESH] |Amino Acid Sequence[MESH] |Antiviral Agents/*chemistry/pharmacology[MESH] |Biological Products/*chemistry/pharmacology[MESH] |Drug Discovery[MESH] |Humans[MESH] |Hydrolyzable Tannins/chemistry[MESH] |Molecular Docking Simulation[MESH] |Plant Extracts/*chemistry/pharmacology[MESH] |Protein Binding[MESH] |Quercetin/chemistry[MESH] |SARS-CoV-2/*drug effects[MESH] |Spike Glycoprotein, Coronavirus/chemistry[MESH] |Triterpenes/chemistry[MESH] |Ursolic Acid[MESH]Potent antiviral activity of Agrimonia pilosa, Galla rhois, and their (epmc).pdf DeepDyve Pubget Overpricing