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suck abstract from ncbi


10.1016/j.clineuro.2021.106834

http://scihub22266oqcxt.onion/10.1016/j.clineuro.2021.106834
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suck abstract from ncbi

pmid34329810      Clin+Neurol+Neurosurg 2021 ; 208 (?): 106834
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  • Myasthenia gravis associated with novel coronavirus 2019 infection: A report of three cases #MMPMID34329810
  • Karimi N; Okhovat AA; Ziaadini B; Haghi Ashtiani B; Nafissi S; Fatehi F
  • Clin Neurol Neurosurg 2021[Sep]; 208 (?): 106834 PMID34329810show ga
  • Several neurological presentations have been reported following coronavirus 2019 (COVID-19) infection. This case report describes three myasthenia gravis (MG) patients presented following COVID-19 infection. We report three adult patients with myasthenic Gravis and COVID-19 infection. The patients are between 38 and 61 years old. Case 1 is a 61-year-old woman with progressive dysphagia, nasal speech, ocular ptosis, diplopia, and proximal muscle weakness for 10 days. She had a COVID-19 infection 6 weeks ago. Case 2 is a 57-year-old man with clinical symptoms of muscular fatigability, diplopia, ptosis, and dysphagia for a week and a positive COVID-19 infection 10 days ago. Case 3 is a 38-year-old woman with fatigability, ptosis, dysphagia, and a diagnosis of COVID-19 infection 4 weeks ago. All patients had a positive RT-PCR for COVID-19 infection by nasopharyngeal swab test and a high-level acetylcholine receptor antibody in the serum. All patients were treated with pyridostigmine and prednisolone with a favorable outcome. MG may appear following COVID-19 infection, and the role of molecular mimicry and latent MG activation should be considered the cause of the disease onset.
  • |Adult[MESH]
  • |Anti-Inflammatory Agents/therapeutic use[MESH]
  • |Autoantibodies/blood/immunology[MESH]
  • |Autoantigens/immunology[MESH]
  • |COVID-19/*complications/immunology[MESH]
  • |Cholinesterase Inhibitors/therapeutic use[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Myasthenia Gravis/drug therapy/immunology/*virology[MESH]
  • |Prednisolone/therapeutic use[MESH]
  • |Receptors, Cholinergic/immunology[MESH]


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