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Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Am+J+Stem+Cells 2021 ; 10 (2): 18-27 Nephropedia Template TP
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Hematopoietic stem and progenitor cells directly participate in host immune response #MMPMID34327049
Daramola OJ; Osasan S; Ali H; Emeagi P
Am J Stem Cells 2021[]; 10 (2): 18-27 PMID34327049show ga
The properties of hematopoietic stem and progenitor cells (HSPCs), including self-renewal and pluripotency, have been extensively studied. These features have been explored in the management of several haematological disorders and malignancies. Although their role as precursors of innate immune cells is well understood, little is known about their direct participation in host immune response. In this review, we explicate the direct role of HSPCs in the host immune response and highlight therapeutic options for the infectious disease burden that is currently ravaging the world, including COVID-19.