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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Front+Endocrinol+(Lausanne) 2021 ; 12 (ä): 690222 Nephropedia Template TP
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The Effect of Lockdown and Physical Activity on Glycemic Control in Italian Children and Young Patients With Type 1 Diabetes #MMPMID34326814
Minuto N; Bassi M; Montobbio C; Vinci F; Mercuri C; Perri FN; Cabri M; Calevo MG; d'Annunzio G; Maghnie M
Front Endocrinol (Lausanne) 2021[]; 12 (ä): 690222 PMID34326814show ga
AIMS: The purpose of the study was to evaluate the impact of the lockdown established by the Italian government to limit the spread of Coronavirus disease (COVID-19) on glycemic control in a large sample of patients with type 1 diabetes (T1D) based on age, type of insulin therapy, number of telemedicine visits and physical activity. MATERIAL AND METHODS: We retrospectively evaluated glycemic control in young T1D patients using the DexcomG6((R)) system before the Italian lockdown (February 10-23, 2020-Time 0) and during lockdown (April 17-30, 2020-Time 1). Data on age, type of insulin therapy, number of telemedicine visits and physical activity of 202 patients with T1D and a median age of 18.2 years (range: 6-39) were collected. RESULTS: Data showed a significant improvement of TIR from 54.58% at T0 to 59.09% at T1 (p =0.0001). Glycemic control improved significantly in patients >/=14 years old, showing the best outcome in the "university students and young adults" group (55.40% at T0 and 61.37% at T1, p =0.001). All patients reduced physical activity during lockdown; in the 56 patients of "intense physical activity" group both at T0 and T1 TIR increased from +/-56.91 to 64.11% (p =0.0001). CONCLUSIONS: Overall, the lockdown led to an unexpected improvement in glycemic control of young patients with T1D. A healthier and stressless lifestyle changes in association with the maintenance of physical activity resulted in a significant age-proportional improvement in glycemic control.
|*Exercise[MESH]
|Adolescent[MESH]
|Adult[MESH]
|COVID-19/epidemiology[MESH]
|Child[MESH]
|Child, Preschool[MESH]
|Diabetes Mellitus, Type 1/*metabolism/*physiopathology[MESH]