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10.1038/s41467-021-24940-w http://scihub22266oqcxt.onion/10.1038/s41467-021-24940-w 34326336!8322155!34326336     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2021 ; 12 (1): 4677 Nephropedia Template TP {{tp|p=34326336|t=2021. Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection |pdf=|usr=}}{{34326336}} gab.com Text Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=34326336 #FOAvip SARS-CoV-2 infection can affect all human beings, including pregnant women. Thus, understanding the immunological changes induced by the virus during pregnancy is nowadays of pivotal importance. Here, using peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection, we investigate cell proliferation and cytokine production, measure plasma levels of 62 cytokines, and perform a 38-parameter mass cytometry analysis. Our results show an increase in low density neutrophils but no lymphopenia or gross alterations of white blood cells, which display normal levels of differentiation, activation or exhaustion markers and show well preserved functionality. Meanwhile, the plasma levels of anti-inflammatory cytokines such as interleukin (IL)-1RA, IL-10 and IL-19 are increased, those of IL-17, PD-L1 and D-dimer are decreased, but IL-6 and other inflammatory molecules remain unchanged. Our profiling of antiviral immune responses may thus help develop therapeutic strategies to avoid virus-induced damages during pregnancy. Twit Text FOAVip Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=34326336 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34326336 #FOAvip English Wikipedia <ref>{{Cite pmid|34326336}}</ref> Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection #MMPMID34326336 De Biasi S; Tartaro DL; Gibellini L; Paolini A; Quong A; Petes C; Awong G; Douglas S; Lin D; Nieto J; Galassi FM; Borella R; Fidanza L; Mattioli M; Leone C; Neri I; Meschiari M; Cicchetti L; Iannone A; Trenti T; Sarti M; Girardis M; Guaraldi G; Mussini C; Facchinetti F; Cossarizza A Nat Commun 2021[Jul]; 12 (1): 4677 PMID34326336show ga SARS-CoV-2 infection can affect all human beings, including pregnant women. Thus, understanding the immunological changes induced by the virus during pregnancy is nowadays of pivotal importance. Here, using peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection, we investigate cell proliferation and cytokine production, measure plasma levels of 62 cytokines, and perform a 38-parameter mass cytometry analysis. Our results show an increase in low density neutrophils but no lymphopenia or gross alterations of white blood cells, which display normal levels of differentiation, activation or exhaustion markers and show well preserved functionality. Meanwhile, the plasma levels of anti-inflammatory cytokines such as interleukin (IL)-1RA, IL-10 and IL-19 are increased, those of IL-17, PD-L1 and D-dimer are decreased, but IL-6 and other inflammatory molecules remain unchanged. Our profiling of antiviral immune responses may thus help develop therapeutic strategies to avoid virus-induced damages during pregnancy. |Adolescent[MESH] |Adult[MESH] |Asymptomatic Infections[MESH] |Biomarkers/blood[MESH] |COVID-19/blood/*immunology/virology[MESH] |Case-Control Studies[MESH] |Cross-Sectional Studies[MESH] |Cytokines/*blood/immunology[MESH] |Female[MESH] |Humans[MESH] |Inflammation/blood/*immunology/prevention & control/virology[MESH] |Middle Aged[MESH] |Pregnancy[MESH] |Pregnancy Complications, Infectious/blood/*immunology/*virology[MESH] |SARS-CoV-2/*immunology/isolation & purification[MESH]Endogenous control of inflammation characterizes pregnant women with a(epmc).pdf DeepDyve Pubget Overpricing