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10.1016/j.cmi.2021.07.020 http://scihub22266oqcxt.onion/10.1016/j.cmi.2021.07.020 34325065!8310783!34325065     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Microbiol+Infect 2021 ; 27 (11): 1700.e1-1700.e3 Nephropedia Template TP {{tp|p=34325065|t=2021. The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons |pdf=|usr=}}{{34325065}} gab.com Text The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons JO: Clin Microbiol Infect http://www.kidney.de/pget.php?&tw=1&pmid=34325065 #FOAvip OBJECTIVES: The aim was to assess the performance of antigen-based rapid diagnostic tests (Ag-RDTs) for SARS CoV-2 when implemented for large-scale universal screening of asymptomatic individuals. METHODS: This study was a pragmatic implementation study for universal Ag-RDT-based screening at a tertiary care hospital in Germany where patients presenting for elective procedures and selected personnel without symptoms suggestive of SARS-CoV-2 were screened with an Ag-RDT since October 2020. Test performance was calculated on an individual patient level. RESULTS: In total, 49 542 RDTs were performed in 27 421 asymptomatic individuals over a duration of 5 and a half months. Out of 222 positive results, 196 underwent in-house confirmatory testing with PCR, out of which 170 were confirmed positive, indicating a positive predictive value of 86.7% (95% CI 81.2-91.1%). Negative Ag-RDTs were not routinely tested with PCR, but a total of 94 cases of false negative Ag-RDTs were detected due to PCR tests being performed within the following 5 days with a median cycle threshold value of 33 (IQR 29-35). DISCUSSION: This study provides evidence that Ag-RDTs can have a high diagnostic yield for transmission relevant infections with limited false positives when utilized at the point of care on asymptomatic patients and thus can be a suitable public health test for universal screening. Twit Text FOAVip The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons ????Clin Microbiol Infect http://www.kidney.de/pget.php?&tw=1&pmid=34325065 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34325065 #FOAvip English Wikipedia <ref>{{Cite pmid|34325065}}</ref> The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons #MMPMID34325065 Wachinger J; Olaru ID; Horner S; Schnitzler P; Heeg K; Denkinger CM Clin Microbiol Infect 2021[Nov]; 27 (11): 1700.e1-1700.e3 PMID34325065show ga OBJECTIVES: The aim was to assess the performance of antigen-based rapid diagnostic tests (Ag-RDTs) for SARS CoV-2 when implemented for large-scale universal screening of asymptomatic individuals. METHODS: This study was a pragmatic implementation study for universal Ag-RDT-based screening at a tertiary care hospital in Germany where patients presenting for elective procedures and selected personnel without symptoms suggestive of SARS-CoV-2 were screened with an Ag-RDT since October 2020. Test performance was calculated on an individual patient level. RESULTS: In total, 49 542 RDTs were performed in 27 421 asymptomatic individuals over a duration of 5 and a half months. Out of 222 positive results, 196 underwent in-house confirmatory testing with PCR, out of which 170 were confirmed positive, indicating a positive predictive value of 86.7% (95% CI 81.2-91.1%). Negative Ag-RDTs were not routinely tested with PCR, but a total of 94 cases of false negative Ag-RDTs were detected due to PCR tests being performed within the following 5 days with a median cycle threshold value of 33 (IQR 29-35). DISCUSSION: This study provides evidence that Ag-RDTs can have a high diagnostic yield for transmission relevant infections with limited false positives when utilized at the point of care on asymptomatic patients and thus can be a suitable public health test for universal screening. |*COVID-19/diagnosis[MESH] |*SARS-CoV-2/isolation & purification[MESH] |Antigens, Viral/*isolation & purification[MESH] |COVID-19 Testing/methods[MESH] |Diagnostic Tests, Routine[MESH] |Germany[MESH] |Humans[MESH] |Mass Screening/*methods[MESH] |Predictive Value of Tests[MESH] |Sensitivity and Specificity[MESH]The potential of SARS-CoV-2 antigen-detection tests in the screening o(epmc).pdf DeepDyve Pubget Overpricing