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Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Front+Pediatr 2021 ; 9 (ä): 647880 Nephropedia Template TP
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Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown #MMPMID34322460
Rasmussen MI; Hansen ML; Pichler G; Dempsey E; Pellicer A; El-Khuffash A; A S; Piris-Borregas S; Alsina M; Cetinkaya M; Chalak L; Ozkan H; Baserga M; Sirc J; Fuchs H; Ergenekon E; Arruza L; Mathur A; Stocker M; Otero Vaccarello O; Szczapa T; Sarafidis K; Krolak-Olejnik B; Memisoglu A; Reigstad H; Rafinska-Wazny E; Hatzidaki E; Peng Z; Gkentzi D; Viellevoye R; De Buyst J; Mastretta E; Wang P; Hahn GH; Bender L; Cornette L; Tkaczyk J; Del Rio R; Fumagalli M; Papathoma E; Wilinska M; Naulaers G; Sadowska-Krawczenko I; Lecart C; Couce ML; Fredly S; Heuchan AM; Karen T; Greisen G
Front Pediatr 2021[]; 9 (ä): 647880 PMID34322460show ga
Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019. Design: This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information: (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman. Results: The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (-6.6%, 95% CI -18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019). Conclusion: This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration: ClinicalTrial.gov, identifier: NCT04527601 (registered August 26, 2020), https://clinicaltrials.gov/ct2/show/NCT04527601.
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Front+Pediatr 2021 ; 9 (ä): 647880
