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suck abstract from ncbi


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pmid34316344      J+Surg+Case+Rep 2021 ; 2021 (7): rjab301
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  • Fatal attraction: intestinal amebiasis and COVID-19 as risk factors for colonic perforation #MMPMID34316344
  • Dorantes JA; Lopez-Becerril JO; Zavala-Cerna MG
  • J Surg Case Rep 2021[Jul]; 2021 (7): rjab301 PMID34316344show ga
  • The parasite Entamoeba histolytica, the causal agent of amebiasis, is considered a worldwide emergent disease and still represents an important cause of death in Mexico. Here, we describe a clinical case, involving an inflammatory response to both Coronavirus Infectious Disease 2019 (COVID-19) and intestinal amebiasis 54-year-old, COVID-positive Mexican gentleman was admitted to surgery following 6 days of hematochezia. An exploratory laparotomy and colonoscopy revealed multiple fibrous and amebic ulcerations (5-10 cm in diameter), with necrotic tissue predominantly localized in the sigmoid, descending and ascending colon. We discuss the pathophysiological interplay of both COVID-19 and intestinal amebiasis with the aim of highlighting a potentially novel aggravating mechanism in surgical patients suffering from colonic perforation in the setting of abdominal sepsis.
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