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10.1016/j.jaut.2021.102687 http://scihub22266oqcxt.onion/10.1016/j.jaut.2021.102687 34311142!8282479!34311142     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Autoimmun 2021 ; 123 (ä): 102687 Nephropedia Template TP {{tp|p=34311142|t=2021. COVID-19 infection among autoimmune rheumatic disease patients: Data from an observational study and literature review |pdf=|usr=}}{{34311142}} gab.com Text COVID-19 infection among autoimmune rheumatic disease patients: Data from an observational study and literature review JO: J Autoimmun http://www.kidney.de/pget.php?&tw=1&pmid=34311142 #FOAvip The impact of SARS-CoV-2 infection in patients with autoimmune/auto-inflammatory rheumatic diseases (AARD) under immunomodulatory treatment has been a focus of interest during the COVID-19 pandemic. In this observational study, demographic data, disease related features and comorbidities, COVID-19 manifestations and outcome as well as antibody responses to SARS-CoV-2 were recorded among 77 consecutive patients with underlying AARD infected by SARS-CoV-2. Analysis of data was performed using univariate and multivariate models. Most patients (68.8%) had a mild COVID-19 course. The predominant clinical manifestations were fatigue (58.4%), low grade fever (45.4%) and upper respiratory tract symptoms (68.8%). About a quarter of patients required hospitalization (23.3%) and the mortality rate was 1.3%. Regarding COVID-19 severity, prior treatment with corticosteroids, mycophenolate mofetil or rituximab was more common in patients who developed a more serious disease course (60.0 vs 29.9%, p = 0.003, 40.0 vs 7.5%, p = 0.003, 10.0 vs 0.0%, p = 0.009, respectively). When disease related features and comorbidities were considered in multivariate models, older age and lung disease in the context of the AARD were found to be independent predictive factors for hospitalization (OR [95%]: 1.09 [1.03-1.15] and 6.43 [1.11-37.19]). Among COVID-19 related features, patients with shortness of breath and high-grade fever were more likely to get hospitalized (OR [95%]: 7.06 [1.36-36.57], 12.04 [2.96-48.86]), while anosmia was independently associated with lower hospitalization risk (OR [95%]: 0.09 [0.01-0.99]). Though the majority of AARD patients displayed a mild COVID-19 course, certain underlying disease features and COVID-19 related manifestations should prompt alertness for the physician to identify patients with AARD at high risk for severe COVID-19 and need for hospitalization. Twit Text FOAVip COVID-19 infection among autoimmune rheumatic disease patients: Data from an observational study and literature review ????J Autoimmun http://www.kidney.de/pget.php?&tw=1&pmid=34311142 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34311142 #FOAvip English Wikipedia <ref>{{Cite pmid|34311142}}</ref> COVID-19 infection among autoimmune rheumatic disease patients: Data from an observational study and literature review #MMPMID34311142 Bakasis AD; Mavragani CP; Boki KA; Tzioufas AG; Vlachoyiannopoulos PG; Stergiou IE; Skopouli FN; Moutsopoulos HM J Autoimmun 2021[Sep]; 123 (ä): 102687 PMID34311142show ga The impact of SARS-CoV-2 infection in patients with autoimmune/auto-inflammatory rheumatic diseases (AARD) under immunomodulatory treatment has been a focus of interest during the COVID-19 pandemic. In this observational study, demographic data, disease related features and comorbidities, COVID-19 manifestations and outcome as well as antibody responses to SARS-CoV-2 were recorded among 77 consecutive patients with underlying AARD infected by SARS-CoV-2. Analysis of data was performed using univariate and multivariate models. Most patients (68.8%) had a mild COVID-19 course. The predominant clinical manifestations were fatigue (58.4%), low grade fever (45.4%) and upper respiratory tract symptoms (68.8%). About a quarter of patients required hospitalization (23.3%) and the mortality rate was 1.3%. Regarding COVID-19 severity, prior treatment with corticosteroids, mycophenolate mofetil or rituximab was more common in patients who developed a more serious disease course (60.0 vs 29.9%, p = 0.003, 40.0 vs 7.5%, p = 0.003, 10.0 vs 0.0%, p = 0.009, respectively). When disease related features and comorbidities were considered in multivariate models, older age and lung disease in the context of the AARD were found to be independent predictive factors for hospitalization (OR [95%]: 1.09 [1.03-1.15] and 6.43 [1.11-37.19]). Among COVID-19 related features, patients with shortness of breath and high-grade fever were more likely to get hospitalized (OR [95%]: 7.06 [1.36-36.57], 12.04 [2.96-48.86]), while anosmia was independently associated with lower hospitalization risk (OR [95%]: 0.09 [0.01-0.99]). Though the majority of AARD patients displayed a mild COVID-19 course, certain underlying disease features and COVID-19 related manifestations should prompt alertness for the physician to identify patients with AARD at high risk for severe COVID-19 and need for hospitalization. |*SARS-CoV-2/immunology[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Antibodies, Viral/biosynthesis[MESH] |Asymptomatic Infections/epidemiology[MESH] |Autoimmune Diseases/drug therapy/*epidemiology/immunology[MESH] |COVID-19/*epidemiology[MESH] |Comorbidity[MESH] |Connective Tissue Diseases/drug therapy/*epidemiology/immunology[MESH] |Critical Illness[MESH] |Female[MESH] |Greece/epidemiology[MESH] |Hospitalization/statistics & numerical data[MESH] |Humans[MESH] |Hypothyroidism/epidemiology[MESH] |Immunocompromised Host[MESH] |Immunoglobulin G/biosynthesis[MESH] |Immunologic Factors/adverse effects/therapeutic use[MESH] |Immunosuppressive Agents/adverse effects/therapeutic use[MESH] |Inflammation[MESH] |Lung Diseases/epidemiology[MESH] |Male[MESH] |Middle Aged[MESH] |Observational Studies as Topic[MESH] |Review Literature as Topic[MESH] |Rheumatic Diseases/drug therapy/epidemiology[MESH] |Severity of Illness Index[MESH]COVID-19 infection among autoimmune rheumatic disease patients: Data f(epmc).pdf DeepDyve Pubget Overpricing