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10.1371/journal.pcbi.1009149

http://scihub22266oqcxt.onion/10.1371/journal.pcbi.1009149
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34310589!8341708!34310589
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suck abstract from ncbi


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pmid34310589      PLoS+Comput+Biol 2021 ; 17 (7): e1009149
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  • Covasim: An agent-based model of COVID-19 dynamics and interventions #MMPMID34310589
  • Kerr CC; Stuart RM; Mistry D; Abeysuriya RG; Rosenfeld K; Hart GR; Nunez RC; Cohen JA; Selvaraj P; Hagedorn B; George L; Jastrzebski M; Izzo AS; Fowler G; Palmer A; Delport D; Scott N; Kelly SL; Bennette CS; Wagner BG; Chang ST; Oron AP; Wenger EA; Panovska-Griffiths J; Famulare M; Klein DJ
  • PLoS Comput Biol 2021[Jul]; 17 (7): e1009149 PMID34310589show ga
  • The COVID-19 pandemic has created an urgent need for models that can project epidemic trends, explore intervention scenarios, and estimate resource needs. Here we describe the methodology of Covasim (COVID-19 Agent-based Simulator), an open-source model developed to help address these questions. Covasim includes country-specific demographic information on age structure and population size; realistic transmission networks in different social layers, including households, schools, workplaces, long-term care facilities, and communities; age-specific disease outcomes; and intrahost viral dynamics, including viral-load-based transmissibility. Covasim also supports an extensive set of interventions, including non-pharmaceutical interventions, such as physical distancing and protective equipment; pharmaceutical interventions, including vaccination; and testing interventions, such as symptomatic and asymptomatic testing, isolation, contact tracing, and quarantine. These interventions can incorporate the effects of delays, loss-to-follow-up, micro-targeting, and other factors. Implemented in pure Python, Covasim has been designed with equal emphasis on performance, ease of use, and flexibility: realistic and highly customized scenarios can be run on a standard laptop in under a minute. In collaboration with local health agencies and policymakers, Covasim has already been applied to examine epidemic dynamics and inform policy decisions in more than a dozen countries in Africa, Asia-Pacific, Europe, and North America.
  • |*COVID-19/etiology/prevention & control/transmission[MESH]
  • |*Models, Biological[MESH]
  • |*SARS-CoV-2[MESH]
  • |*Systems Analysis[MESH]
  • |Basic Reproduction Number[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Computational Biology[MESH]
  • |Computer Simulation[MESH]
  • |Contact Tracing[MESH]
  • |Disease Progression[MESH]
  • |Hand Disinfection[MESH]
  • |Host Microbial Interactions[MESH]
  • |Humans[MESH]
  • |Masks[MESH]
  • |Mathematical Concepts[MESH]
  • |Pandemics[MESH]
  • |Physical Distancing[MESH]
  • |Quarantine[MESH]


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