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10.1099/jmm.0.001372

http://scihub22266oqcxt.onion/10.1099/jmm.0.001372
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34309503!8493423!34309503
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suck abstract from ncbi


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pmid34309503      J+Med+Microbiol 2021 ; 70 (7): ä
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  • Acceptable performance of the Abbott ID NOW among symptomatic individuals with confirmed COVID-19 #MMPMID34309503
  • Stokes W; Berenger BM; Singh T; Adeghe I; Schneider A; Portnoy D; King T; Scott B; Pabbaraju K; Shokoples S; Wong AA; Gill K; Turnbull L; Hu J; Tipples G
  • J Med Microbiol 2021[Jul]; 70 (7): ä PMID34309503show ga
  • Introduction. The ID NOW is FDA approved for the detection of SARS-CoV-2 in symptomatic individuals within the first 7 days of symptom onset for COVID-19 if tested within 1 h of specimen collection.Gap statement. Clinical data on the performance of the ID NOW are limited, with many studies varying in their study design and/or having small sample size.Aim. In this study we aimed to determine the clinical performance of the ID NOW compared to conventional RT-PCR testing.Methodology. Adults with COVID-19 in the community or hospital were recruited into the study. Paired throat swabs were collected, with one throat swab transported immediately in an empty sterile tube to the laboratory for ID NOW testing, and the other transported in universal transport media and tested by an in-house SARS-CoV-2 RT-PCR assay targeting the E gene.Results. In total, 133 individuals were included in the study; 129 samples were positive on either the ID NOW and/or RT-PCR. Assuming any positive result on either assay represents a true positive, positive per cent agreement (PPA) of the ID NOW compared to RT-PCR with 95 % confidence intervals was 89.1 % (82.0-94.1%) and 91.6 % (85.1-95.9%), respectively. When analysing individuals with symptom duration
  • |*COVID-19 Nucleic Acid Testing[MESH]
  • |Adult[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |False Negative Reactions[MESH]
  • |False Positive Reactions[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Nucleic Acid Amplification Techniques[MESH]
  • |Reproducibility of Results[MESH]


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