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10.4274/tjh.galenos.2021.2021.0277

http://scihub22266oqcxt.onion/10.4274/tjh.galenos.2021.2021.0277
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34308605!8656133!34308605
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suck abstract from ncbi


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pmid34308605      Turk+J+Haematol 2021 ; 38 (4): 321-324
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  • Convalescent Plasma Reduces Endogenous Antibody Response in COVID-19: A Retrospective Cross-Sectional Study #MMPMID34308605
  • Omma A; Erden A; Guven SC; Ates I; Kucuksahin O
  • Turk J Haematol 2021[Dec]; 38 (4): 321-324 PMID34308605show ga
  • OBJECTIVE: The aim of this study is to investigate post-COVID-19 antibody titers in patients who received convalescent plasma (CP) in addition to standard-of-care treatment. MATERIALS AND METHODS: Hospitalized COVID-19 patients who received CP in addition to standard care were retrospectively investigated. Patients who received CP with a recorded total COVID-19 antibody test result after treatment were included. From among hospitalized COVID-19 patients who received only standard care with a recorded total COVID-19 antibody test result, a control group matched for age, gender, and comorbidities was formed. Total COVID-19 antibody index levels were compared. RESULTS: Thirty-three CP recipients were enrolled in the study. The control group consisted of 34 age-, gender-, and comorbidity-matched standard-care patients. Median total COVID-19 antibody index levels were significantly reduced in the CP group. CONCLUSION: Although CP therapy may have benefits for disease outcome, its potential ability to hamper long-term immunity may be a problem.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibody Formation[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |COVID-19/blood/*diagnosis/*therapy[MESH]
  • |Case-Control Studies[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Immunization, Passive[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]


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