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10.2217/fvl-2021-0058

http://scihub22266oqcxt.onion/10.2217/fvl-2021-0058
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34306167!8293688!34306167
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suck abstract from ncbi


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pmid34306167      Future+Virol 2021 ; ä (ä): ä
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  • An overview of sex hormones in relation to SARS-CoV-2 infection #MMPMID34306167
  • Ghare Naz MS; Banaei M; Dashti S; Tehrani FR
  • Future Virol 2021[Jul]; ä (ä): ä PMID34306167show ga
  • Aim: Sex differences in COVID-19 outcomes might be explained from a sex hormones (SexHs) perspective. Materials & methods: PubMed, Scopus, Web of Science, EMBASE and Google Scholar were searched up to March 2021. Results: Based on the literature review, the crosstalk between SexHs (estrogens, progesterone and testosterone), their receptors (estrogen alpha and beta, androgen, and progesterone) and the immune system shaped the sex-related differences in immune responses against COVID-19. Differential production of SexHs over the lifespan (during pregnancy, reproductive years, menopause and andropause) and over different seasons may result in disparities in body response toward COVID-19. Moreover, SexHs-specific differences might affect vaccine efficacy and response to treatment. Conclusion: The roles of SexHs need to be considered in vaccine development and even treatment of COVID-19.
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