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10.1007/s12288-021-01472-3

http://scihub22266oqcxt.onion/10.1007/s12288-021-01472-3
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suck abstract from ncbi


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pmid34305341      Indian+J+Hematol+Blood+Transfus 2022 ; 38 (2): 388-393
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  • Outcomes of COVID-19 in Hematopoietic Stem Cell Transplant Recipients: Multicenter Retrospective Analysis #MMPMID34305341
  • Agrawal N; Singh R; Sharma SK; Naithani R; Bhargava R; Choudhary D; Jeyaraman P; Bansal S; Doval D; Khandelwal V; Bansal N; Ahmed R; Bhurani D
  • Indian J Hematol Blood Transfus 2022[Apr]; 38 (2): 388-393 PMID34305341show ga
  • COVID-19, caused by the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), was declared a pandemic by the World Health Organization on March 9, 2020. Hematopoietic stem-cell transplantation (HSCT) recipients may be highly susceptible to infection and related pulmonary complications due to nascent immune systems or organ damage from treatment-related toxicities. Poor outcomes in such group of patients were linked to older age, steroid therapy at the time of COVID-19 infection, and COVID-19 infection within a year of HSCT. We studied a cohort of 28 hematopoietic stem cell transplant recipients (male 17, M:F ratio of 1.5) with COVID-19 infection from 1st June 2020, through 31st December 2020 for outcome. Fever was the most common symptom at the time of presentation in 22 (78.5%) patients. Mortality rate at Day 28 and Day 42 was found to be 4/28 (14.3%) and 7/28 (25%) respectively. Patients within one year of HSCT and severe infection had higher day 28 mortality (with p values = 0.038)". There was no relation of mortality with type of transplant.
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