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10.1055/s-0041-1732320 http://scihub22266oqcxt.onion/10.1055/s-0041-1732320 34298578!ä!34298578 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Pediatr+Surg 2022 ; 32 (3): 240-250 Nephropedia Template TP {{tp|p=34298578|t=2022. Determination of Factors to Distinguish MIS-C from Acute Appendicitis in Children with Acute Abdominal Pain |pdf=|usr=}}{{34298578}} gab.com Text Determination of Factors to Distinguish MIS-C from Acute Appendicitis in Children with Acute Abdominal Pain JO: Eur J Pediatr Surg http://www.kidney.de/pget.php?&tw=1&pmid=34298578 #FOAvip INTRODUCTION: The aim of this study was to make the differential diagnosis between acute appendicitis and multisystem inflammatory syndrome in children (MIS-C) for patients presenting with the complaint of acute abdominal pain (AAP) and to identify the determining factors for the diagnosis of MIS-C. MATERIALS AND METHODS: Eighty-one children presenting with AAP/suspected AAP were evaluated. Of these, 24 (29.6%) were included in the MIS-C group (MIS-C/g) and 57 were included in the suspected appendicitis group (S-A/g), which consisted of two subgroups: appendicitis group (A/g) and control observation group (CO/g). RESULTS: Comparing MIS-C/g, A/g, and CO/g, duration of abdominal pain (2.4, 1.5, 1.8 days), high-grade fever (38.8, 36.7, 37 degrees C), severe vomiting, and severe diarrhea were higher in MIS-C/g. Lymphocytes count (LC) was lower, while values of C-reactive protein (CRP), ferritin, and coagulopathy were higher in MIS-C/g (p < 0.05). The optimal cutoffs for the duration of abdominal pain was 2.5 days; the duration of fever, 1.5 days; peak value of fever, 39 degrees C; neutrophil count, 13,225 x 1,000 cell/microMoL; LC, 600 x 1,000 cell/microMoL; ferritin, 233 microg/L; and D-dimer, 16.4 mg/L (p < 0.05). The optimal cutoff for CRP was 130 mg/L (sensitivity 88.9, specificity 100%, positive predictive value 100%, NPV, negative predictive value 92.5%, p < 0.001). All patients in MIS-C/g tested positive by serology by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CONCLUSION: The duration of abdominal pain, presence of high-grade and prolonged fever, and evaluation of hemogram in terms of high neutrophil count and low LC exhibit high sensitivity and negative predictive value for MIS-C presenting with AAP. In case of doubt, inflammatory markers such as CRP, ferritin, D-dimer, and serology for SARS-CoV-2 should be studied to confirm the diagnosis. Twit Text FOAVip Determination of Factors to Distinguish MIS-C from Acute Appendicitis in Children with Acute Abdominal Pain ????Eur J Pediatr Surg http://www.kidney.de/pget.php?&tw=1&pmid=34298578 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34298578 #FOAvip English Wikipedia <ref>{{Cite pmid|34298578}}</ref> Determination of Factors to Distinguish MIS-C from Acute Appendicitis in Children with Acute Abdominal Pain #MMPMID34298578 Azili MN; Guney D; Oztorun CI; Erturk A; Erten EE; Demir S; Ertoy A; Emeksiz S; Parlakay AO; Celikel BA; Senel E Eur J Pediatr Surg 2022[Jun]; 32 (3): 240-250 PMID34298578show ga INTRODUCTION: The aim of this study was to make the differential diagnosis between acute appendicitis and multisystem inflammatory syndrome in children (MIS-C) for patients presenting with the complaint of acute abdominal pain (AAP) and to identify the determining factors for the diagnosis of MIS-C. MATERIALS AND METHODS: Eighty-one children presenting with AAP/suspected AAP were evaluated. Of these, 24 (29.6%) were included in the MIS-C group (MIS-C/g) and 57 were included in the suspected appendicitis group (S-A/g), which consisted of two subgroups: appendicitis group (A/g) and control observation group (CO/g). RESULTS: Comparing MIS-C/g, A/g, and CO/g, duration of abdominal pain (2.4, 1.5, 1.8 days), high-grade fever (38.8, 36.7, 37 degrees C), severe vomiting, and severe diarrhea were higher in MIS-C/g. Lymphocytes count (LC) was lower, while values of C-reactive protein (CRP), ferritin, and coagulopathy were higher in MIS-C/g (p < 0.05). The optimal cutoffs for the duration of abdominal pain was 2.5 days; the duration of fever, 1.5 days; peak value of fever, 39 degrees C; neutrophil count, 13,225 x 1,000 cell/microMoL; LC, 600 x 1,000 cell/microMoL; ferritin, 233 microg/L; and D-dimer, 16.4 mg/L (p < 0.05). The optimal cutoff for CRP was 130 mg/L (sensitivity 88.9, specificity 100%, positive predictive value 100%, NPV, negative predictive value 92.5%, p < 0.001). All patients in MIS-C/g tested positive by serology by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CONCLUSION: The duration of abdominal pain, presence of high-grade and prolonged fever, and evaluation of hemogram in terms of high neutrophil count and low LC exhibit high sensitivity and negative predictive value for MIS-C presenting with AAP. In case of doubt, inflammatory markers such as CRP, ferritin, D-dimer, and serology for SARS-CoV-2 should be studied to confirm the diagnosis. |*Appendicitis/complications/diagnosis[MESH] |*COVID-19/complications/diagnosis[MESH] |*Systemic Inflammatory Response Syndrome/diagnosis[MESH] |Abdominal Pain/diagnosis/etiology[MESH] |Acute Disease[MESH] |C-Reactive Protein[MESH] |Child[MESH] |Diagnosis, Differential[MESH] |Ferritins[MESH] |Fever[MESH] |Humans[MESH]Determination of Factors to Distinguish MIS-C from Acute Appendicitis (epmc).pdf DeepDyve Pubget Overpricing