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10.1016/j.diabres.2021.108953

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suck abstract from ncbi


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pmid34298043      Diabetes+Res+Clin+Pract 2021 ; 178 (ä): 108953
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  • Diabetes mellitus as a risk factor for SARS-CoV-2 test positivity in Mexico: A propensity score matched study #MMPMID34298043
  • Seiglie JA; Servan-Mori E; Manne-Goehler J; Meigs JB; Miranda JJ; Sosa-Rubi SG; Silverman-Retana O; Wexler DJ; Wirtz VJ
  • Diabetes Res Clin Pract 2021[Aug]; 178 (ä): 108953 PMID34298043show ga
  • AIMS: We sought to investigate whether individuals with diabetes have a higher likelihood of testing positive for SARS-CoV-2, as a proxy for infection risk, than individuals without diabetes. METHODS: We conducted a cross-sectional study of publicly available data among a Mexican population, totaling 2,314,022 adults?>/=?18?years who underwent SARS-CoV-2 testing between March 1 and December 20, 2020. We used 1:1 nearest neighborhood propensity score matching by diabetes status to account for confounding among those with and without diabetes. RESULTS: In the overall study population, 1,057,779 (45.7%) individuals tested positive for SARS-CoV-2 and 270,486 (11.7%) self-reported diabetes. After propensity score matching, patient characteristics were well-balanced, with 150,487 patients in the diabetes group (mean [SD] age 55.9 [12.7] years; 51.3% women) and 150,487 patients in the no diabetes group (55.5 [13.3] years; 50.3% women). The strictest matching algorithm (1:1 nearest neighbor) showed that compared to individuals without diabetes, having diabetes was associated with 9.0% higher odds of having a positive SARS-CoV-2 test (OR 1.09 [95% CI: 1.08-1.10]). CONCLUSIONS: Presence of diabetes was associated with higher odds of testing positive for SARS-CoV-2, which could have important implications for risk mitigation efforts for people with diabetes at risk of SARS-CoV-2 infection.
  • |*COVID-19/diagnosis[MESH]
  • |*Diabetes Mellitus/epidemiology[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19 Testing[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Mexico/epidemiology[MESH]
  • |Middle Aged[MESH]
  • |Propensity Score[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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