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10.1093/eurjpc/zwab119

http://scihub22266oqcxt.onion/10.1093/eurjpc/zwab119
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34297822!8344916!34297822
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suck abstract from ncbi


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pmid34297822      Eur+J+Prev+Cardiol 2022 ; 29 (8): 1266-1274
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  • Impact of the COVID-19 pandemic on in-hospital mortality in cardiovascular disease: a meta-analysis #MMPMID34297822
  • Cannata A; Watson SA; Daniel A; Giacca M; Shah AM; McDonagh TA; Scott PA; Bromage DI
  • Eur J Prev Cardiol 2022[May]; 29 (8): 1266-1274 PMID34297822show ga
  • AIMS: The COVID-19 pandemic has resulted in excess mortality due to both COVID-19 directly and other conditions, including cardiovascular (CV) disease. We aimed to explore the excess in-hospital mortality, unrelated to COVID-19 infection, across a range of CV diseases. METHODS AND RESULTS: A systematic search was performed for studies investigating in-hospital mortality among patients admitted with CV disease without SARS-CoV-2 infection compared with a period outside the COVID-19 pandemic. Fifteen studies on 27 421 patients with CV disease were included in the analysis. The average in-hospital mortality rate was 10.4% (n = 974) in the COVID-19 group and 5.7% (n = 1026) in the comparator group. Compared with periods outside the COVID-19 pandemic, the pooled risk ratio (RR) demonstrated increased in-hospital mortality by 62% during COVID-19 [95% confidence interval (CI) 1.20-2.20, P = 0.002]. Studies with a decline in admission rate >50% during the COVID-19 pandemic observed the greatest increase in mortality compared with those with <50% reduction [RR 2.74 (95% CI 2.43-3.10) vs. 1.21 (95% CI 1.07-1.37), P < 0.001]. The observed increased mortality was consistent across different CV conditions (P = 0.74 for interaction). CONCLUSIONS: In-hospital mortality among patients admitted with CV diseases was increased relative to periods outside the pandemic, independent of co-infection with COVID-19. This effect was larger in studies with the biggest decline in admission rates, suggesting a sicker cohort of patients in this period. However, studies were generally poorly conducted, and there is a need for further well-designed studies to establish the full extent of mortality not directly related to COVID-19 infection.
  • |*COVID-19[MESH]
  • |*Cardiovascular Diseases/diagnosis[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]


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