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10.1002/mus.27378

http://scihub22266oqcxt.onion/10.1002/mus.27378
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suck abstract from ncbi


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pmid34296433      Muscle+Nerve 2021 ; 64 (4): 474-482
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  • Impact of COVID-19 on the quality of life of patients with neuromuscular disorders in the Lombardy area, Italy #MMPMID34296433
  • Gagliardi D; Costamagna G; Abati E; Mauri E; Brusa R; Scudeller L; Andreoli L; Citterio G; Piccin E; Magri F; Meneri M; Velardo D; Sciacco M; Bresolin N; Corti S; Comi GP
  • Muscle Nerve 2021[Oct]; 64 (4): 474-482 PMID34296433show ga
  • INTRODUCTION: /AIMS: Patients with neuromuscular disorders (NMDs), including many elderly, immunosuppressed, and disabled individuals, may have been particularly affected during the coronavirus disease 2019 (COVID-19) pandemic in Lombardy, a COVID-19 high-incidence area between February and May 2020. We aimed to evaluate the effects of the COVID-19 pandemic on the quality of life (QoL) and perceived disease burden of this group of patients. METHODS: We conducted a cross-sectional phone-based survey study between June 1 and June 14, 2020, on a sample of 240 NMD patients followed at our clinic in Milan, Italy. We asked about perceived NMD burden and QoL before and during the COVID-19 pandemic. We collected responses on access to outpatient care and ancillary services. We investigated the presence of symptoms suggestive of COVID-19 infection and confirmed cases. RESULTS: We collected 205 responses: 53 patients (25.9%) reported a subjective worsening of the underlying NMD. QoL measures showed a significant worsening between pre and pandemic time frames (odds ratio, 2.14 95%; confidence interval, 1.82-2.51). Outpatient visits were postponed in more than half of cases (57.1%), with 104 patients (50.7%) experiencing a cancellation of scheduled diagnostic tests. 79 patients (38.5%) reported at least one symptom attributable to COVID-19 infection. Among the 10 patients tested with nasopharyngeal swabs, 6 tested positive and 3 died from respiratory failure, including 2 patients on corticosteroid/ immunosuppressive therapy. DISCUSSION: The COVID-19 pandemic affected QoL and limited access to outpatient care and ancillary services of NMD patients in Lombardy between February and May 2020.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/diagnosis/*epidemiology/*psychology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Italy/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neuromuscular Diseases/diagnosis/*epidemiology/*psychology[MESH]
  • |Quality of Life/*psychology[MESH]


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