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10.1038/s41522-021-00232-5 http://scihub22266oqcxt.onion/10.1038/s41522-021-00232-5 34294722!8298611!34294722     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       NPJ+Biofilms+Microbiomes 2021 ; 7 (1): 61 Nephropedia Template TP {{tp|p=34294722|t=2021. Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization |pdf=|usr=}}{{34294722}} gab.com Text Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization JO: NPJ Biofilms Microbiomes http://www.kidney.de/pget.php?&tw=1&pmid=34294722 #FOAvip The human oral and gut commensal microbes play vital roles in the development and maintenance of immune homeostasis, while its association with susceptibility and severity of SARS-CoV-2 infection is barely understood. In this study, we investigated the dynamics of the oral and intestinal flora before and after the clearance of SARS-CoV-2 in 53 COVID-19 patients, and then examined their microbiome alterations in comparison to 76 healthy individuals. A total of 140 throat swab samples and 81 fecal samples from these COVID-19 patients during hospitalization, and 44 throat swab samples and 32 fecal samples from sex and age-matched healthy individuals were collected and then subjected to 16S rRNA sequencing and viral load inspection. We found that SARS-CoV-2 infection was associated with alterations of the microbiome community in patients as indicated by both alpha and beta diversity indexes. Several bacterial taxa were identified related to SARS-CoV-2 infection, wherein elevated Granulicatella and Rothia mucilaginosa were found in both oral and gut microbiome. The SARS-CoV-2 viral load in those samples was also calculated to identify potential dynamics between COVID-19 and the microbiome. These findings provide a meaningful baseline for microbes in the digestive tract of COVID-19 patients and will shed light on new dimensions for disease pathophysiology, potential microbial biomarkers, and treatment strategies for COVID-19. Twit Text FOAVip Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization ????NPJ Biofilms Microbiomes http://www.kidney.de/pget.php?&tw=1&pmid=34294722 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34294722 #FOAvip English Wikipedia <ref>{{Cite pmid|34294722}}</ref> Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization #MMPMID34294722 Wu Y; Cheng X; Jiang G; Tang H; Ming S; Tang L; Lu J; Guo C; Shan H; Huang X NPJ Biofilms Microbiomes 2021[Jul]; 7 (1): 61 PMID34294722show ga The human oral and gut commensal microbes play vital roles in the development and maintenance of immune homeostasis, while its association with susceptibility and severity of SARS-CoV-2 infection is barely understood. In this study, we investigated the dynamics of the oral and intestinal flora before and after the clearance of SARS-CoV-2 in 53 COVID-19 patients, and then examined their microbiome alterations in comparison to 76 healthy individuals. A total of 140 throat swab samples and 81 fecal samples from these COVID-19 patients during hospitalization, and 44 throat swab samples and 32 fecal samples from sex and age-matched healthy individuals were collected and then subjected to 16S rRNA sequencing and viral load inspection. We found that SARS-CoV-2 infection was associated with alterations of the microbiome community in patients as indicated by both alpha and beta diversity indexes. Several bacterial taxa were identified related to SARS-CoV-2 infection, wherein elevated Granulicatella and Rothia mucilaginosa were found in both oral and gut microbiome. The SARS-CoV-2 viral load in those samples was also calculated to identify potential dynamics between COVID-19 and the microbiome. These findings provide a meaningful baseline for microbes in the digestive tract of COVID-19 patients and will shed light on new dimensions for disease pathophysiology, potential microbial biomarkers, and treatment strategies for COVID-19. |*Viral Load[MESH] |Bacteria/classification/genetics[MESH] |COVID-19/diagnosis/*microbiology/virology[MESH] |Feces/microbiology[MESH] |Female[MESH] |Gastrointestinal Microbiome/*physiology[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |Mouth/microbiology[MESH] |RNA, Ribosomal, 16S[MESH]Altered oral and gut microbiota and its association with SARS-CoV-2 vi(epmc).pdf DeepDyve Pubget Overpricing