Effects of Treatment of Coronavirus Disease 2019 With Convalescent Plasma in 25 B-Cell-Depleted Patients #MMPMID34293119
Gharbharan A; GeurtsvanKessel CH; Jordans CCE; Blaauw M; van der Klift M; Hassing RJ; Smits-Zwinkels M; Meertens M; van den Hout EC; de Man AM; Hageman I; Bogers S; van der Schoot CE; Swaneveld F; Anas AA; Rokx C; Rijnders BJA
Clin Infect Dis 2022[Apr]; 74 (7): 1271-1274 PMID34293119show ga
Twenty-five B-cell-depleted patients (24 following anti-CD19/20 therapy) diagnosed with coronavirus disease 2019 had been symptomatic for a median of 26 days but remained antibody negative. All were treated with convalescent plasma with high neutralizing antibody titers. Twenty-one (84%) recovered, indicating the potential therapeutic effects of this therapy in this particular population.