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10.1111/j.1472-8206.1987.tb00561.x

http://scihub22266oqcxt.onion/10.1111/j.1472-8206.1987.tb00561.x
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3428842!ä!3428842

suck abstract from ncbi


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pmid3428842      Fundam+Clin+Pharmacol 1987 ; 1 (3): 225-32
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  • Magnesuria induced by thiazides and the influence of triamterene #MMPMID3428842
  • Labeeuw M; Pozet N; Zech P; Hadj-Aissa A; Sassard J
  • Fundam Clin Pharmacol 1987[]; 1 (3): 225-32 PMID3428842show ga
  • The effects on magnesium excretion of 4 short-term diuretic treatments (methyclothiazide 2 mg either alone or associated with increasing doses of triamterene) were evaluated in 8 normal volunteers and compared to spontaneous variations during placebo administration. The thiazide exerted a small but significant magnesuric effect, which was prevented only by the lowest dose (25 mg) of triamterene. Larger doses had no protective effect on thiazide-induced magnesuria. Independently of their absolute effects on magnesium excretion, all diuretics impaired the normal ability of the kidneys to compensate fully for the expected changes in magnesium reabsorption induced by extracellular volume contraction.
  • |*Benzothiadiazines[MESH]
  • |Adult[MESH]
  • |Diuretics[MESH]
  • |Drug Interactions[MESH]
  • |Humans[MESH]
  • |Magnesium/*urine[MESH]
  • |Male[MESH]
  • |Sodium Chloride Symporter Inhibitors/*adverse effects[MESH]


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