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10.1590/0004-282X-ANP-2021-0030

http://scihub22266oqcxt.onion/10.1590/0004-282X-ANP-2021-0030
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34287509!ä!34287509

suck abstract from ncbi


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pmid34287509      Arq+Neuropsiquiatr 2021 ; 79 (10): 924-928
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  • Peripheral neuropathy in COVID-19 is due to immune-mechanisms, pre-existing risk factors, anti-viral drugs, or bedding in the Intensive Care Unit #MMPMID34287509
  • Finsterer J; Scorza FA; Scorza CA; Fiorini AC
  • Arq Neuropsiquiatr 2021[Oct]; 79 (10): 924-928 PMID34287509show ga
  • BACKGROUND: This mini-review aims to summarize and discuss previous and recent advances in the clinical presentation, pathophysiology, diagnosis, treatment, and outcome of SARS-CoV-2-associated peripheral neuropathies. METHODS: Literature review. RESULTS: Altogether, 105 articles about SARS-CoV-2-associated neuropathy describing 261 patients were retrieved. Peripheral neuropathy in patients with COVID-19 is frequent and predominantly due to immune mechanisms or neurotoxic side effects of drugs used to treat the symptoms of COVID-19 and, to a lesser extent, due to the compression of peripheral nerves resulting from prolonged bedding in the Intensive Care Unit (ICU) and pre-existing risk factors such as diabetes. SARS-CoV-2 does not cause viral neuropathy. Neurotoxic drugs such as daptomycin, linezolid, lopinavir, ritonavir, hydro-chloroquine, cisatracurium, clindamycin, and glucocorticoids should be administered with caution and patients should be appropriately bedded in the ICU to prevent SARS-CoV-2-associated neuropathy. Patients with Guillain-Barre syndrome (GBS) benefit from immunoglobulins, plasma exchange, and steroids. CONCLUSIONS: Neuropathies of peripheral nerves in patients with COVID-19 are frequent and mostly result from immune mechanisms or neurotoxic side effects of drugs used to treat the symptoms of COVID-19 and, to a lesser extent, from the compression of peripheral nerves due to prolonged bedding on the ICU. SARS-CoV-2 does not cause infectious neuropathy.
  • |*COVID-19[MESH]
  • |*Guillain-Barre Syndrome/chemically induced[MESH]
  • |*Peripheral Nervous System Diseases/chemically induced[MESH]
  • |*Pharmaceutical Preparations[MESH]
  • |Antiviral Agents[MESH]
  • |Bedding and Linens[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Risk Factors[MESH]


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