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10.3201/eid2708.210667

http://scihub22266oqcxt.onion/10.3201/eid2708.210667
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suck abstract from ncbi


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pmid34286681      Emerg+Infect+Dis 2021 ; 27 (8): 2081-2089
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  • Effects of Patient Characteristics on Diagnostic Performance of Self-Collected Samples for SARS-CoV-2 Testing #MMPMID34286681
  • Smith-Jeffcoat SE; Koh M; Hoffman A; Rebolledo PA; Schechter MC; Miller HK; Sleweon S; Rossetti R; Kasinathan V; Shragai T; O'Laughlin K; Espinosa CC; Khalil GM; Adeyemo AO; Moorman A; Bauman BL; Joseph K; O'Hegarty M; Kamal N; Atallah H; Moore BL; Bohannon CD; Bankamp B; Hartloge C; Bowen MD; Paulick A; Gargis AS; Elkins C; Stewart RJ; da Silva J; Biedron C; Tate JE; Wang YF; Kirking HL
  • Emerg Infect Dis 2021[]; 27 (8): 2081-2089 PMID34286681show ga
  • We evaluated the performance of self-collected anterior nasal swab (ANS) and saliva samples compared with healthcare worker-collected nasopharyngeal swab specimens used to test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We used the same PCR diagnostic panel to test all self-collected and healthcare worker-collected samples from participants at a public hospital in Atlanta, Georgia, USA. Among 1,076 participants, 51.9% were men, 57.1% were >50 years of age, 81.2% were Black (non-Hispanic), and 74.9% reported >1 chronic medical condition. In total, 8.0% tested positive for SARS-CoV-2. Compared with nasopharyngeal swab samples, ANS samples had a sensitivity of 59% and saliva samples a sensitivity of 68%. Among participants tested 3-7 days after symptom onset, ANS samples had a sensitivity of 80% and saliva samples a sensitivity of 85%. Sensitivity varied by specimen type and patient characteristics. These findings can help physicians interpret PCR results for SARS-CoV-2.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19 Testing[MESH]
  • |Georgia[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Nasopharynx[MESH]
  • |Saliva[MESH]


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