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10.1177/00220345211029269 http://scihub22266oqcxt.onion/10.1177/00220345211029269 34282982!ä!34282982 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Dent+Res 2021 ; 100 (11): 1265-1272 Nephropedia Template TP {{tp|p=34282982|t=2021. Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro |pdf=|usr=}}{{34282982}} gab.com Text Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro JO: J Dent Res http://www.kidney.de/pget.php?&tw=1&pmid=34282982 #FOAvip Oral mouthwashes decrease the infectivity of several respiratory viruses including SARS-CoV-2. However, the precise agents with antiviral activity in these oral rinses and their exact mechanism of action remain unknown. Here we show that cetylpyridinium chloride (CPC), a quaternary ammonium compound in many oral mouthwashes, reduces SARS-CoV-2 infectivity by inhibiting the viral fusion step with target cells after disrupting the integrity of the viral envelope. We also found that CPC-containing mouth rinses decreased more than a thousand times the infectivity of SARS-CoV-2 in vitro, while the corresponding vehicles had no effect. This activity was effective for different SARS-CoV-2 variants, including the B.1.1.7 or Alpha variant originally identified in United Kingdom, and in the presence of sterilized saliva. CPC-containing mouth rinses could therefore represent a cost-effective measure to reduce SARS-CoV-2 infectivity in saliva, aiding to reduce viral transmission from infected individuals regardless of the variants they are infected with. Twit Text FOAVip Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro ????J Dent Res http://www.kidney.de/pget.php?&tw=1&pmid=34282982 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34282982 #FOAvip English Wikipedia <ref>{{Cite pmid|34282982}}</ref> Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro #MMPMID34282982 Munoz-Basagoiti J; Perez-Zsolt D; Leon R; Blanc V; Raich-Regue D; Cano-Sarabia M; Trinite B; Pradenas E; Blanco J; Gispert J; Clotet B; Izquierdo-Useros N J Dent Res 2021[Oct]; 100 (11): 1265-1272 PMID34282982show ga Oral mouthwashes decrease the infectivity of several respiratory viruses including SARS-CoV-2. However, the precise agents with antiviral activity in these oral rinses and their exact mechanism of action remain unknown. Here we show that cetylpyridinium chloride (CPC), a quaternary ammonium compound in many oral mouthwashes, reduces SARS-CoV-2 infectivity by inhibiting the viral fusion step with target cells after disrupting the integrity of the viral envelope. We also found that CPC-containing mouth rinses decreased more than a thousand times the infectivity of SARS-CoV-2 in vitro, while the corresponding vehicles had no effect. This activity was effective for different SARS-CoV-2 variants, including the B.1.1.7 or Alpha variant originally identified in United Kingdom, and in the presence of sterilized saliva. CPC-containing mouth rinses could therefore represent a cost-effective measure to reduce SARS-CoV-2 infectivity in saliva, aiding to reduce viral transmission from infected individuals regardless of the variants they are infected with. |*COVID-19[MESH] |*Mouthwashes/pharmacology[MESH] |Cetylpyridinium/pharmacology[MESH] |Humans[MESH]Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In (epmc).pdf DeepDyve Pubget Overpricing