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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Adv+Exp+Med+Biol 2021 ; 1327 (ä): 197-204 Nephropedia Template TP
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Curcumin and Piperine in COVID-19: A Promising Duo to the Rescue? #MMPMID34279840
Miryan M; Soleimani D; Askari G; Jamialahmadi T; Guest PC; Bagherniya M; Sahebkar A
Adv Exp Med Biol 2021[]; 1327 (ä): 197-204 PMID34279840show ga
COVID-19 is now pandemic throughout the world, and scientists are searching for effective therapies to prevent or treat the disease. The combination of curcumin and piperine is a potential option for the management of COVID-19 based on several mechanisms including antiviral, anti-inflammatory, immunomodulatory, antifibrotic, and antioxidant effects. Here, we describe the probable mechanism of curcumin-piperine against COVID-19. Administration of curcumin-piperine combination appears as a potential strategy to counterbalance the pathophysiological features of COVID-19 including inflammation. The optimal dose and duration of curcumin-piperine supplementation should be determined in the future.