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10.1177/15353702211024651 http://scihub22266oqcxt.onion/10.1177/15353702211024651 34279137!8647481!34279137     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Exp+Biol+Med+(Maywood) 2021 ; 246 (23): 2495-2501 Nephropedia Template TP {{tp|p=34279137|t=2021. Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil |pdf=|usr=}}{{34279137}} gab.com Text Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil JO: Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=34279137 #FOAvip In this cross-sectional study, we investigate the presence of Severe Acute Respiratory Syndrome Coronavirus 2 Ribonucleic Acid (SARS-CoV-2 RNA) in the tears of hospitalized COVID-19 patients. After laboratory confirmation of SARS-CoV-2 infection by reverse transcription polymerase chain reaction (RT-PCR) analysis, tear samples from both eyes of each patient were collected using conjunctival swab for RT-PCR. Detailed demographic profile, systemic and ocular symptoms, comorbidities, clinical, ancillary, and ocular manifestations were evaluated. Of the 83 patients enrolled in the study, 7 (8.43%) had SARS-CoV-2 RNA detected in the tear samples. Neutrophils' count, C-reactive protein, and D-dimer were higher in patients with SARS-CoV-2 detected in tears than in patients without virus in ocular surface samples. One patient with SARS-CoV-2 in tears showed mild ocular eyelid edema, hyperemia, and chemosis. No relevant ocular manifestations were detected in the other patients. Although the levels of viral RNA on ocular surface samples were low for most patients (5/7), with positivity only for gene N and CT higher than 30, two patients were positive for all viral targets tested (N, E, and RpRd), with viral load near 1 x 10(5) ePFU/mL, indicating that the ocular transmission of SARS-CoV-2 is a possibility that needs to be considered, especially in the hospital environment. Further studies need to be conducted to demonstrate whether infective viral particles could be isolated from tears. Twit Text FOAVip Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil ????Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=34279137 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34279137 #FOAvip English Wikipedia <ref>{{Cite pmid|34279137}}</ref> Identification of SARS-CoV-2 on the ocular surface in a cohort of COVID-19 patients from Brazil #MMPMID34279137 Gasparini MS; Dos Santos LM; Hamade AM; Gross LG; Favarato AP; de Vasconcellos JP; de Melo MB; Parise PL; Simeoni CL; Silva NB; da Silva Mori MA; Vieira AS; Dos Santos Farias A; Granja F; Schreiber AZ; Moretti ML; Proenca-Modena JL; Alves M Exp Biol Med (Maywood) 2021[Dec]; 246 (23): 2495-2501 PMID34279137show ga In this cross-sectional study, we investigate the presence of Severe Acute Respiratory Syndrome Coronavirus 2 Ribonucleic Acid (SARS-CoV-2 RNA) in the tears of hospitalized COVID-19 patients. After laboratory confirmation of SARS-CoV-2 infection by reverse transcription polymerase chain reaction (RT-PCR) analysis, tear samples from both eyes of each patient were collected using conjunctival swab for RT-PCR. Detailed demographic profile, systemic and ocular symptoms, comorbidities, clinical, ancillary, and ocular manifestations were evaluated. Of the 83 patients enrolled in the study, 7 (8.43%) had SARS-CoV-2 RNA detected in the tear samples. Neutrophils' count, C-reactive protein, and D-dimer were higher in patients with SARS-CoV-2 detected in tears than in patients without virus in ocular surface samples. One patient with SARS-CoV-2 in tears showed mild ocular eyelid edema, hyperemia, and chemosis. No relevant ocular manifestations were detected in the other patients. Although the levels of viral RNA on ocular surface samples were low for most patients (5/7), with positivity only for gene N and CT higher than 30, two patients were positive for all viral targets tested (N, E, and RpRd), with viral load near 1 x 10(5) ePFU/mL, indicating that the ocular transmission of SARS-CoV-2 is a possibility that needs to be considered, especially in the hospital environment. Further studies need to be conducted to demonstrate whether infective viral particles could be isolated from tears. |Adult[MESH] |Aged[MESH] |Brazil[MESH] |COVID-19 Nucleic Acid Testing/statistics & numerical data[MESH] |COVID-19/complications/pathology/*virology[MESH] |Eye Infections, Viral/epidemiology/pathology/*virology[MESH] |Eye/*virology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |SARS-CoV-2/genetics/*pathogenicity[MESH] |Tears/virology[MESH]Identification of SARS-CoV-2 on the ocular surface in a cohort of COVI(epmc).pdf DeepDyve Pubget Overpricing