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10.1016/j.jaip.2021.06.045 http://scihub22266oqcxt.onion/10.1016/j.jaip.2021.06.045 34273582!8279920!34273582     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Allergy+Clin+Immunol+Pract 2021 ; 9 (9): 3237-3248 Nephropedia Template TP {{tp|p=34273582|t=2021. SARS-CoV-2 Infection in the Immunodeficient Host: Necessary and Dispensable Immune Pathways |pdf=|usr=}}{{34273582}} gab.com Text SARS-CoV-2 Infection in the Immunodeficient Host: Necessary and Dispensable Immune Pathways JO: J Allergy Clin Immunol Pract http://www.kidney.de/pget.php?&tw=1&pmid=34273582 #FOAvip Since its outbreak in late December 2019 in Wuhan, coronavirus disease 2019 pandemic has posed a therapeutic challenge for the world population, with a plenty of clinical pictures and a broad spectrum of severity of the manifestations. In spite of initial speculations on a direct role of primary or acquired immune deficiency in determining a worse disease outcome, recent studies have provided evidence that specific immune defects may either serve as an experimentum naturae entailing this risk or may not be relevant enough to impact the host defense against the virus. Taken together, these observations may help unveil pathogenetic mechanisms of the infection and suggest new therapeutic strategies. Thus, in this review, we summarize current knowledge regarding the mechanisms of immune response against severe acute respiratory syndrome coronavirus 2 infection and clinical manifestations with a special focus on children and patients presenting with congenital or acquired immune deficiency. Twit Text FOAVip SARS-CoV-2 Infection in the Immunodeficient Host: Necessary and Dispensable Immune Pathways ????J Allergy Clin Immunol Pract http://www.kidney.de/pget.php?&tw=1&pmid=34273582 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34273582 #FOAvip English Wikipedia <ref>{{Cite pmid|34273582}}</ref> SARS-CoV-2 Infection in the Immunodeficient Host: Necessary and Dispensable Immune Pathways #MMPMID34273582 Giardino G; Romano R; Coppola E; Cillo F; Borzachiello C; De Luca M; Palamaro L; Toriello E; Prencipe R; Cirillo E; Pignata C J Allergy Clin Immunol Pract 2021[Sep]; 9 (9): 3237-3248 PMID34273582show ga Since its outbreak in late December 2019 in Wuhan, coronavirus disease 2019 pandemic has posed a therapeutic challenge for the world population, with a plenty of clinical pictures and a broad spectrum of severity of the manifestations. In spite of initial speculations on a direct role of primary or acquired immune deficiency in determining a worse disease outcome, recent studies have provided evidence that specific immune defects may either serve as an experimentum naturae entailing this risk or may not be relevant enough to impact the host defense against the virus. Taken together, these observations may help unveil pathogenetic mechanisms of the infection and suggest new therapeutic strategies. Thus, in this review, we summarize current knowledge regarding the mechanisms of immune response against severe acute respiratory syndrome coronavirus 2 infection and clinical manifestations with a special focus on children and patients presenting with congenital or acquired immune deficiency. |*COVID-19[MESH] |*Immunologic Deficiency Syndromes[MESH] |Child[MESH] |Disease Outbreaks[MESH] |Humans[MESH] |Pandemics[MESH]SARS-CoV-2 Infection in the Immunodeficient Host: Necessary and Dispen(epmc).pdf DeepDyve Pubget Overpricing