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10.24875/GMM.20000498

http://scihub22266oqcxt.onion/10.24875/GMM.20000498
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34270530!ä!34270530

suck abstract from ncbi


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pmid34270530      Gac+Med+Mex 2021 ; 157 (2): 174-180
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  • Antigenos del sistema sanguineo ABO como factor de riesgo para la gravedad de la infeccion por SARS-CoV-2 #MMPMID34270530
  • Torres-Alarcon CG; Garcia-Ruiz A; Canete-Ibanez CR; Morales-Pogoda II; Munoz-Arce CM; Cid-Dominguez BE; Montalvo-Barcenas M; Torre GM; Sandoval-Lopez C; Gaytan-Guzman E; Correo-Zamora JD
  • Gac Med Mex 2021[]; 157 (2): 174-180 PMID34270530show ga
  • INTRODUCTION: Whether there is an influence of the ABO blood system on SARS-CoV-2 infection is unknown. OBJECTIVE: To analyze if there is an association between the ABO system antigens and susceptibility to and severity of SARS-CoV-2 infection. MATERIAL AND METHODS: The frequency of ABO system antigens was compared in 73 confirmed cases of SARS-CoV-2 infection and 52 clinically healthy donors. Infection severity was assessed by comparing the frequency of antigens by disease severity and mortality. RESULTS: The risk of suffering from SARS-CoV-2 infection increases in subjects with A vs. non-A antigen (OR = 1.45; 95 % CI: 1.061-1.921). Blood phenotype O reduces the risk of SARS-CoV-2 infection (OR = 0.686; 95 % CI: 0.522-0.903). No differences were found regarding disease severity. In critically ill patients, the risk of mortality increased in subjects with A vs. non-A antigen (OR = 3.34; 95 % CI: 1.417-8.159). CONCLUSION: Blood group A is a risk factor for SARS-CoV-2 infection, but not for disease severity, although in critically ill patients it is a risk factor for mortality.
  • |*Severity of Illness Index[MESH]
  • |ABO Blood-Group System/adverse effects/*immunology[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/blood/epidemiology/*immunology/mortality[MESH]
  • |Case-Control Studies[MESH]
  • |Confidence Intervals[MESH]
  • |Critical Illness[MESH]
  • |Disease Susceptibility/blood/immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Odds Ratio[MESH]
  • |Risk Factors[MESH]


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