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10.1007/s10072-021-05444-3

http://scihub22266oqcxt.onion/10.1007/s10072-021-05444-3
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34264414!8280630!34264414
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suck abstract from ncbi


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pmid34264414      Neurol+Sci 2021 ; 42 (10): 3965-3968
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  • New daily persistent headache after SARS-CoV-2 infection: a report of two cases #MMPMID34264414
  • Dono F; Consoli S; Evangelista G; D'Apolito M; Russo M; Carrarini C; Calisi D; De Rosa M; Di Pietro M; De Angelis MV; Travaglini D; Sensi SL; Onofrj M; Bonanni L
  • Neurol Sci 2021[Oct]; 42 (10): 3965-3968 PMID34264414show ga
  • BACKGROUND: The 2019 Coronavirus (SARS-CoV-2) is a novel respiratory virus which causes Coronavirus Disease19 (COVID-19). Although the predominant clinical picture of COVID-19 is represented by respiratory symptoms, neurological manifestations are being increasingly recognized. Headache, in particular migraine-like and tension types, has been largely reported in patients suffering from COVID-19 both in the acute and the healing phase of the infection. New daily persistent headache (NDPH) is a primary headache characterized by persistent and daily painful symptoms, with pain becoming continuous and non-remitting within 24 h, and lasting more than 3 months. Even though an increasing number of reports describe patients who develop a persistent headache, diagnosis of NPDH has been rarely explored in the context of COVID-19. METHODS: Two patients with persistent headache and Sars-CoV-2 infection were identified. Both underwent a full clinical and neuroradiological evaluation. Blood sample with inflammatory biomarkers search was also performed. RESULTS: According to International Classifications of Headache Disorders diagnosis of probable new daily persistent headache was made. The treatment with high doses of steroids was associated with relief of symptoms. CONCLUSIONS: Our report described two cases of probable NDPH due to SARS-CoV-2 infection. Clinical evaluation of COVID-19 patients presenting with persistent headache should take into consideration NDPH. Given the supposed major role for neuroinflammation in the genesis of Sars-CoV-2-driven NDPH, immunomodulatory therapy should be promptly started. In line with this hypothesis, we obtained a good therapeutic response to short-term high dose of corticosteroids.
  • |*COVID-19[MESH]
  • |*Headache Disorders/diagnosis/drug therapy/etiology[MESH]
  • |*Migraine Disorders[MESH]
  • |Headache/drug therapy/etiology[MESH]
  • |Humans[MESH]


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