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10.3389/fmed.2021.697605 http://scihub22266oqcxt.onion/10.3389/fmed.2021.697605 34262921!8273171!34262921     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Med+(Lausanne) 2021 ; 8 (ä): 697605 Nephropedia Template TP {{tp|p=34262921|t=2021. Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K |pdf=|usr=}}{{34262921}} gab.com Text Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K JO: Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=34262921 #FOAvip COVID-19 pandemics has led to genetic diversification of SARS-CoV-2 and the appearance of variants with potential impact in transmissibility and viral escape from acquired immunity. We report a new and highly divergent lineage containing 21 distinctive mutations (10 non-synonymous, eight synonymous, and three substitutions in non-coding regions). The amino acid changes L249S and E484K located at the CTD and RBD of the Spike protein could be of special interest due to their potential biological role in the virus-host relationship. Further studies are required for monitoring the epidemiologic impact of this new lineage. Twit Text FOAVip Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K ????Front Med (Lausanne) http://www.kidney.de/pget.php?&tw=1&pmid=34262921 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34262921 #FOAvip English Wikipedia <ref>{{Cite pmid|34262921}}</ref> Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K #MMPMID34262921 Laiton-Donato K; Usme-Ciro JA; Franco-Munoz C; Alvarez-Diaz DA; Ruiz-Moreno HA; Reales-Gonzalez J; Prada DA; Corchuelo S; Herrera-Sepulveda MT; Naizaque J; Santamaria G; Wiesner M; Walteros DM; Ospina Martinez ML; Mercado-Reyes M Front Med (Lausanne) 2021[]; 8 (ä): 697605 PMID34262921show ga COVID-19 pandemics has led to genetic diversification of SARS-CoV-2 and the appearance of variants with potential impact in transmissibility and viral escape from acquired immunity. We report a new and highly divergent lineage containing 21 distinctive mutations (10 non-synonymous, eight synonymous, and three substitutions in non-coding regions). The amino acid changes L249S and E484K located at the CTD and RBD of the Spike protein could be of special interest due to their potential biological role in the virus-host relationship. Further studies are required for monitoring the epidemiologic impact of this new lineage. äNovel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions(epmc).pdf DeepDyve Pubget Overpricing