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10.1371/journal.pone.0254456 http://scihub22266oqcxt.onion/10.1371/journal.pone.0254456 34260633!8279349!34260633     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34260633&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       PLoS+One 2021 ; 16 (7): e0254456 Nephropedia Template TP {{tp|p=34260633|t=2021. The impact of vaccination to control COVID-19 burden in the United States: A simulation modeling approach |pdf=|usr=}}{{34260633}} gab.com Text The impact of vaccination to control COVID-19 burden in the United States: A simulation modeling approach JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=34260633 #FOAvip INTRODUCTION: Vaccination programs aim to control the COVID-19 pandemic. However, the relative impacts of vaccine coverage, effectiveness, and capacity in the context of nonpharmaceutical interventions such as mask use and physical distancing on the spread of SARS-CoV-2 are unclear. Our objective was to examine the impact of vaccination on the control of SARS-CoV-2 using our previously developed agent-based simulation model. METHODS: We applied our agent-based model to replicate COVID-19-related events in 1) Dane County, Wisconsin; 2) Milwaukee metropolitan area, Wisconsin; 3) New York City (NYC). We evaluated the impact of vaccination considering the proportion of the population vaccinated, probability that a vaccinated individual gains immunity, vaccination capacity, and adherence to nonpharmaceutical interventions. We estimated the timing of pandemic control, defined as the date after which only a small number of new cases occur. RESULTS: The timing of pandemic control depends highly on vaccination coverage, effectiveness, and adherence to nonpharmaceutical interventions. In Dane County and Milwaukee, if 50% of the population is vaccinated with a daily vaccination capacity of 0.25% of the population, vaccine effectiveness of 90%, and the adherence to nonpharmaceutical interventions is 60%, controlled spread could be achieved by June 2021 versus October 2021 in Dane County and November 2021 in Milwaukee without vaccine. DISCUSSION: In controlling the spread of SARS-CoV-2, the impact of vaccination varies widely depending not only on effectiveness and coverage, but also concurrent adherence to nonpharmaceutical interventions. Twit Text FOAVip The impact of vaccination to control COVID-19 burden in the United States: A simulation modeling approach ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=34260633 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34260633 #FOAvip English Wikipedia <ref>{{Cite pmid|34260633}}</ref> The impact of vaccination to control COVID-19 burden in the United States: A simulation modeling approach #MMPMID34260633 Alagoz O; Sethi AK; Patterson BW; Churpek M; Alhanaee G; Scaria E; Safdar N PLoS One 2021[]; 16 (7): e0254456 PMID34260633show ga INTRODUCTION: Vaccination programs aim to control the COVID-19 pandemic. However, the relative impacts of vaccine coverage, effectiveness, and capacity in the context of nonpharmaceutical interventions such as mask use and physical distancing on the spread of SARS-CoV-2 are unclear. Our objective was to examine the impact of vaccination on the control of SARS-CoV-2 using our previously developed agent-based simulation model. METHODS: We applied our agent-based model to replicate COVID-19-related events in 1) Dane County, Wisconsin; 2) Milwaukee metropolitan area, Wisconsin; 3) New York City (NYC). We evaluated the impact of vaccination considering the proportion of the population vaccinated, probability that a vaccinated individual gains immunity, vaccination capacity, and adherence to nonpharmaceutical interventions. We estimated the timing of pandemic control, defined as the date after which only a small number of new cases occur. RESULTS: The timing of pandemic control depends highly on vaccination coverage, effectiveness, and adherence to nonpharmaceutical interventions. In Dane County and Milwaukee, if 50% of the population is vaccinated with a daily vaccination capacity of 0.25% of the population, vaccine effectiveness of 90%, and the adherence to nonpharmaceutical interventions is 60%, controlled spread could be achieved by June 2021 versus October 2021 in Dane County and November 2021 in Milwaukee without vaccine. DISCUSSION: In controlling the spread of SARS-CoV-2, the impact of vaccination varies widely depending not only on effectiveness and coverage, but also concurrent adherence to nonpharmaceutical interventions. |COVID-19 Vaccines/*therapeutic use[MESH] |COVID-19/*prevention & control[MESH] |Computer Simulation[MESH] |Humans[MESH] |Masks[MESH] |Patient Compliance/*statistics & numerical data[MESH] |Physical Distancing[MESH] |Respiratory Protective Devices/statistics & numerical data[MESH] |United States[MESH] |Urban Health[MESH]The impact of vaccination to control COVID-19 burden in the United Sta(epmc).pdf DeepDyve Pubget Overpricing