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10.1080/09537104.2021.1952179

http://scihub22266oqcxt.onion/10.1080/09537104.2021.1952179
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34260328!ä!34260328

suck abstract from ncbi


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pmid34260328      Platelets 2022 ; 33 (2): 200-207
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  • Platelet-leukocyte interactions in the pathogenesis of viral infections #MMPMID34260328
  • Hottz ED; Quirino-Teixeira AC; Merij LB; Pinheiro MBM; Rozini SV; Bozza FA; Bozza PT
  • Platelets 2022[Feb]; 33 (2): 200-207 PMID34260328show ga
  • Evolving evidence demonstrates that platelets have major roles in viral syndromes through previously unrecognized viral sensing and effector functions. Activated platelets and increased platelet-leukocyte aggregates are observed in clinical and experimental viral infections. The mechanisms and outcomes of platelet-leukocyte interactions depend on the interacting leukocyte as well as on the pathogen and pathological conditions. In this review, we discuss the mechanisms involved in platelet interactions with leukocytes and its functions during viral infections. We focus on the contributions of human platelet-leukocyte interactions to pathophysiological and protective responses during viral infections of major global health relevance, including acquired immunodeficiency syndrome (AIDS), dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), influenza pneumonia, and COVID-19.
  • |Blood Platelets/*metabolism[MESH]
  • |Humans[MESH]
  • |Leukocytes/*metabolism[MESH]


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