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10.1590/1806-9282.67.Suppl1.20200754

http://scihub22266oqcxt.onion/10.1590/1806-9282.67.Suppl1.20200754
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34259769!ä!34259769

suck abstract from ncbi


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pmid34259769      Rev+Assoc+Med+Bras+(1992) 2021 ; 67Suppl 1 (Suppl 1): 127-156
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  • Potential impact of the COVID-19 in HIV-infected individuals: a systematic review Impact of the COVID-19 in HIV-Infected Individuals #MMPMID34259769
  • de Medeiros KS; da Silva LAS; Macedo LTA; Sarmento AC; Costa APF; Eleuterio J Jr; Goncalves AK
  • Rev Assoc Med Bras (1992) 2021[]; 67Suppl 1 (Suppl 1): 127-156 PMID34259769show ga
  • BACKGROUND: Although much has been studied about the SARS-Cov-2 virus, its effects, and the effectiveness of possible treatments, little is known about its interaction with other infectious diseases. OBJECTIVE: The aim is to study its clinical features and morbidity, and mortality outcomes of COVID-19 patients with HIV/AIDS coinfection. DATA SOURCES: MEDLINE, Web of Science, Embase, CINAHL, LILACS, Scopus, ClinicalTrials.gov, and Cochrane. STUDY ELIGIBILITY CRITERIA: Atudies in any language, published after 2019, were describing COVID-19 patients with HIV/AIDS. STUDY APPRAISAL: JBI Levels of Evidence, Joanna Briggs Institute. SYNTHESIS METHODS: As shown in the PRISMA flow diagram, two authors separately screened the search results from the obtained titles and abstracts. RESULTS: Chest CT was observed in patients with pneumonia by SARS-CoV-2 with findings of multiple ground-glass opacities (GGO) in the lungs, there is a need for supplemental oxygenation. One patient developed encephalopathy and complicated tonic-clonic seizures; four patients were transplanted (two, liver; two, kidneys), one patient developed severe SARS-CoV-2 pneumonia and 30 patients died (mortality rate, 11%). CONCLUSION: HIV did not show any relevance directly with the occurrence of COVID-19. Some studies suggest that HIV-1 infection through induction levels of IFN-I, may to some extent, stop the apparent SARS-CoV-2 infection, thus leading to undetectable RNA. Moreover, some authors suggest retroviral therapy routinely used to control HIV infection could be used to prevent COVID-19 infection.
  • |*COVID-19[MESH]
  • |*Coinfection[MESH]
  • |*HIV Infections/complications[MESH]
  • |Humans[MESH]


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