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Transplant of SARS-CoV-2-infected Living Donor Liver: Case Report #MMPMID34258388
Nguyen MC; Lee EJ; Avery RK; Dioverti-Prono MV; Shoham S; Tobian AAR; Bloch EM; Gurakar A; Rizkalla NA; Cameron AM; King EA; Ottmann S; Garonzik-Wang JM; Wesson RN; Philosophe B
Transplant Direct 2021[Aug]; 7 (8): e721 PMID34258388show ga
Given the high community prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), transplant programs will encounter SARS-CoV-2 infections in living donors or recipients in the perioperative period. There is limited data on SARS-CoV-2 viremia and organotropism beyond the respiratory tract to inform the risk of transplant transmission of SARS-CoV-2. We report a case of a living donor liver transplant recipient who received a right lobe graft from a living donor with symptomatic PCR-confirmed SARS-CoV-2 infection 3 d following donation. The donor was successfully treated with remdesivir, dexamethasone, and coronavirus disease 2019 (COVID-19) convalescent plasma. No viral transmission was identified, and both donor and recipient had excellent postoperative outcomes.