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10.1016/j.accpm.2021.100931 http://scihub22266oqcxt.onion/10.1016/j.accpm.2021.100931 34256165!8272066!34256165     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Anaesth+Crit+Care+Pain+Med 2021 ; 40 (4): 100931 Nephropedia Template TP {{tp|p=34256165|t=2021. French multicentre observational study on SARS-CoV-2 infections intensive care initial management: the FRENCH CORONA study |pdf=|usr=}}{{34256165}} gab.com Text French multicentre observational study on SARS-CoV-2 infections intensive care initial management: the FRENCH CORONA study JO: Anaesth Crit Care Pain Med http://www.kidney.de/pget.php?&tw=1&pmid=34256165 #FOAvip AIM: Describing acute respiratory distress syndrome patterns, therapeutics management, and outcomes of ICU COVID-19 patients and indentifying risk factors of 28-day mortality. METHODS: Prospective multicentre, cohort study conducted in 29 French ICUs. Baseline characteristics, comorbidities, adjunctive therapies, ventilatory support at ICU admission and survival data were collected. RESULTS: From March to July 2020, 966 patients were enrolled with a median age of 66 (interquartile range 58-73) years and a median SAPS II of 37 (29-48). During the first 24 h of ICU admission, COVID-19 patients received one of the following respiratory supports: mechanical ventilation for 559 (58%), standard oxygen therapy for 228 (24%) and high-flow nasal cannula (HFNC) for 179 (19%) patients. Overall, 721 (75%) patients were mechanically ventilated during their ICU stay. Prone positioning and neuromuscular blocking agents were used in 494 (51%) and 460 (48%) patients, respectively. Bacterial co-infections and ventilator-associated pneumonia were diagnosed in 79 (3%) and 411 (43%) patients, respectively. The overall 28-day mortality was 18%. Age, pre-existing comorbidities, severity of respiratory failure and the absence of antiviral therapy on admission were identified as independent predictors of 28-day outcome. CONCLUSION: Severity of hypoxaemia on admission, older age (> 70 years), cardiovascular and renal comorbidities were associated with worse outcome in COVID-19 patients. Antiviral treatment on admission was identified as a protective factor for 28-day mortality. Ascertaining the outcomes of critically ill COVID-19 patients is crucial to optimise hospital and ICU resources and provide the appropriate intensity level of care. Twit Text FOAVip French multicentre observational study on SARS-CoV-2 infections intensive care initial management: the FRENCH CORONA study ????Anaesth Crit Care Pain Med http://www.kidney.de/pget.php?&tw=1&pmid=34256165 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34256165 #FOAvip English Wikipedia <ref>{{Cite pmid|34256165}}</ref> French multicentre observational study on SARS-CoV-2 infections intensive care initial management: the FRENCH CORONA study #MMPMID34256165 Roger C; Collange O; Mezzarobba M; Abou-Arab O; Teule L; Garnier M; Hoffmann C; Muller L; Lefrant JY; Guinot PG; Novy E; Abraham P; Clavier T; Bourenne J; Besch G; Favier L; Fiani M; Ouattara A; Joannes-Boyau O; Fischer MO; Leone M; Ait Tamlihat Y; Pottecher J; Cordier PY; Aussant P; Moussa MD; Hautin E; Bouex M; Julia JM; Cady J; Danguy Des Deserts M; Mayeur N; Mura T; Allaouchiche B Anaesth Crit Care Pain Med 2021[Aug]; 40 (4): 100931 PMID34256165show ga AIM: Describing acute respiratory distress syndrome patterns, therapeutics management, and outcomes of ICU COVID-19 patients and indentifying risk factors of 28-day mortality. METHODS: Prospective multicentre, cohort study conducted in 29 French ICUs. Baseline characteristics, comorbidities, adjunctive therapies, ventilatory support at ICU admission and survival data were collected. RESULTS: From March to July 2020, 966 patients were enrolled with a median age of 66 (interquartile range 58-73) years and a median SAPS II of 37 (29-48). During the first 24 h of ICU admission, COVID-19 patients received one of the following respiratory supports: mechanical ventilation for 559 (58%), standard oxygen therapy for 228 (24%) and high-flow nasal cannula (HFNC) for 179 (19%) patients. Overall, 721 (75%) patients were mechanically ventilated during their ICU stay. Prone positioning and neuromuscular blocking agents were used in 494 (51%) and 460 (48%) patients, respectively. Bacterial co-infections and ventilator-associated pneumonia were diagnosed in 79 (3%) and 411 (43%) patients, respectively. The overall 28-day mortality was 18%. Age, pre-existing comorbidities, severity of respiratory failure and the absence of antiviral therapy on admission were identified as independent predictors of 28-day outcome. CONCLUSION: Severity of hypoxaemia on admission, older age (> 70 years), cardiovascular and renal comorbidities were associated with worse outcome in COVID-19 patients. Antiviral treatment on admission was identified as a protective factor for 28-day mortality. Ascertaining the outcomes of critically ill COVID-19 patients is crucial to optimise hospital and ICU resources and provide the appropriate intensity level of care. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Aged[MESH] |Cohort Studies[MESH] |Critical Care[MESH] |Humans[MESH] |Intensive Care Units[MESH] |Middle Aged[MESH] |Prospective Studies[MESH]French multicentre observational study on SARS-CoV-2 infections intens(epmc).pdf DeepDyve Pubget Overpricing