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suck abstract from ncbi


10.1177/20587384211031763

http://scihub22266oqcxt.onion/10.1177/20587384211031763
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34250834!8274088!34250834
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suck abstract from ncbi

pmid34250834      Int+J+Immunopathol+Pharmacol 2021 ; 35 (?): 20587384211031763
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  • The effectiveness of Colchicine as an anti-inflammatory drug in the treatment of coronavirus disease 2019: Meta-analysis #MMPMID34250834
  • Golpour M; Mousavi T; Alimohammadi M; Mosayebian A; Shiran M; Alizadeh Navaei R; Rafiei A
  • Int J Immunopathol Pharmacol 2021[Jan]; 35 (?): 20587384211031763 PMID34250834show ga
  • A recently discovered coronavirus, SARS-CoV-2, caused a global respiratory disease pandemic called COVID-19. Many studies have shown the excessive activation of the innate immune response that leads to the adverse outcomes of COVID-19, and anti-inflammatory drugs are very useful in the treatment and management of this infection. The activities of Colchicine, one of the anti-inflammatory drugs, target several pathways related to excessive inflammation of COVID-19. This study aimed to evaluate the efficacy of Colchicine in the treatment of COVID-19 using a meta-analysis approach. Scopus, Pubmed, Google scholars, Web of Science, and Science direct were used to search all the randomized controlled trials, case-control, and cross-sectional studies that have evaluated the efficacy of Colchicine as a treatment for COVID-19 (up to 28 May 2021). The overall effect of Colchicine versus the control group was determined using a random-effects model meta-analysis where we compared changes (i.e. mean differences-Colchicine group vs Control group) between the two conditions in test scores indicative of hospitalization time (day) and mortality rate. The results illustrated Colchicine therapy is associated with a decreased mortality rate in COVID-19 patients and associated with a decrease in hospitalization time (day) in COVID-19 patients. Present preliminary data shows that Colchicine has a beneficial effect on coronavirus disease care in 2019. Therefore, Colchicine can be a good suggestion in the management of COVID-19.
  • |*COVID-19 Drug Treatment[MESH]
  • |Anti-Inflammatory Agents/adverse effects/*therapeutic use[MESH]
  • |COVID-19/diagnosis/mortality/virology[MESH]
  • |Colchicine/adverse effects/*therapeutic use[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Length of Stay[MESH]
  • |Time Factors[MESH]


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