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10.3389/fimmu.2021.680567 http://scihub22266oqcxt.onion/10.3389/fimmu.2021.680567 34248962!8260674!34248962     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2021 ; 12 (ä): 680567 Nephropedia Template TP {{tp|p=34248962|t=2021. Case Report: Adult Post-COVID-19 Multisystem Inflammatory Syndrome and Thrombotic Microangiopathy |pdf=|usr=}}{{34248962}} gab.com Text Case Report: Adult Post-COVID-19 Multisystem Inflammatory Syndrome and Thrombotic Microangiopathy JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=34248962 #FOAvip BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide. A clinical series of Kawasaki-like multisystem inflammatory syndrome (MIS), occurring after SARS-CoV-2 infection, have been described in children (MIS-C) and adults (MIS-A), but the pathophysiology remains unknown. CASE PRESENTATION: We describe a case of post-COVID-19 MIS-A in a 46-year-old man with biopsy-proven renal thrombotic microangiopathy (TMA). Specific complement inhibition with eculizumab was initiated promptly and led to a dramatic improvement of renal function. CONCLUSION: Our case suggests that that TMA could play a central role in the pathophysiology of post-COVID-19 MIS-A, making complement blockers an interesting therapeutic option. Twit Text FOAVip Case Report: Adult Post-COVID-19 Multisystem Inflammatory Syndrome and Thrombotic Microangiopathy ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=34248962 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34248962 #FOAvip English Wikipedia <ref>{{Cite pmid|34248962}}</ref> Case Report: Adult Post-COVID-19 Multisystem Inflammatory Syndrome and Thrombotic Microangiopathy #MMPMID34248962 Boudhabhay I; Rabant M; Roumenina LT; Coupry LM; Poillerat V; Marchal A; Fremeaux-Bacchi V; El Karoui K; Monchi M; Pourcine F Front Immunol 2021[]; 12 (ä): 680567 PMID34248962show ga BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide. A clinical series of Kawasaki-like multisystem inflammatory syndrome (MIS), occurring after SARS-CoV-2 infection, have been described in children (MIS-C) and adults (MIS-A), but the pathophysiology remains unknown. CASE PRESENTATION: We describe a case of post-COVID-19 MIS-A in a 46-year-old man with biopsy-proven renal thrombotic microangiopathy (TMA). Specific complement inhibition with eculizumab was initiated promptly and led to a dramatic improvement of renal function. CONCLUSION: Our case suggests that that TMA could play a central role in the pathophysiology of post-COVID-19 MIS-A, making complement blockers an interesting therapeutic option. |Antibodies, Monoclonal, Humanized/*therapeutic use[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/*diagnosis[MESH] |Complement Inactivating Agents/*therapeutic use[MESH] |Humans[MESH] |Kidney/*metabolism/pathology[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Recovery of Function[MESH] |SARS-CoV-2/*physiology[MESH] |Systemic Inflammatory Response Syndrome/*diagnosis/drug therapy[MESH]Case Report: Adult Post-COVID-19 Multisystem Inflammatory Syndrome and(epmc).pdf DeepDyve Pubget Overpricing