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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 N+Z+Med+J 2021 ; 134 (1538): 44-51 Nephropedia Template TP
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Higher perceived stress and exacerbated motor symptoms in Parkinson s disease during the COVID-19 lockdown in New Zealand #MMPMID34239144
Blakemore RL; Pascoe MJ; Horne KL; Livingston L; Young BN; Elias B; Goulden M; Grenfell S; Myall DJ; Pitcher TL; Dalrymple-Alford JC; Le Heron CJ; Anderson TJ; MacAskill MR
N Z Med J 2021[Jul]; 134 (1538): 44-51 PMID34239144show ga
AIMS: Stress plays a key role in Parkinson's disease (PD) by acting on the dopaminergic system and worsening patients' motor function. The impact of New Zealand's strict lockdown measures to contain COVID-19 on perceived stress and PD motor symptoms remains unknown. Here we examined the relationship between perceived levels of stress, changes in physical activity levels and PD motor symptoms during lockdown. METHODS: During lockdown, 134 participants with PD and 49 controls completed a survey assessing perceived stress, self-reported changes in PD motor symptoms and physical activity duration and intensity prior to and during lockdown. RESULTS: Perceived stress was higher in PD than controls, and in those reporting a worsening of tremor, balance/gait, dyskinesia and bradykinesia compared to those indicating no change during the COVID-19 lockdown. These effects were not modulated by physical activity. CONCLUSIONS: Reducing stressors may be an important adjunct treatment strategy to improve motor function in PD.