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10.2147/TCRM.S313003

http://scihub22266oqcxt.onion/10.2147/TCRM.S313003
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34234442!8254585!34234442
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suck abstract from ncbi


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pmid34234442      Ther+Clin+Risk+Manag 2021 ; 17 (ä): 657-668
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  • Therapeutic Agents Rounding Up the Immunopathology of COVID-19 #MMPMID34234442
  • Li HP; He X; Zhang L; Li CX; Li SQ; Li QY
  • Ther Clin Risk Manag 2021[]; 17 (ä): 657-668 PMID34234442show ga
  • COVID-19 pandemic has caused more than 3 million deaths globally during the past year. The direct attack from SARS-CoV-2 and hyperactivated immune response contribute to the progress and deterioration of COVID-19. After the virus invades, the activation and release of cytokines/chemokines cause "cytokine storm", leading to acute respiratory distress syndrome (ARDS) and multiple organs dysfunction syndrome (MODS). Eliminating virus and blocking cytokines are important checkpoints of COVID-19 therapy, and several agents targeting immunopathology, including interferons, thymosin, glucocorticoids and immunoglobulin, have shown therapeutic effects in severe patients with COVID-19. Herein, we reviewed the practice evidences and concluded that several agents rounding up the immunopathology of COVID-19 may be the alternative approaches under the scenario of the lacking of effective antiviral drugs.
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